SCHEMBL6330348

SCHEMBL6330348

[CH](/C=C/[CH]c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.56
ALDH1A1 P00352 4/20 0.47
TSHR P16473 1/20 0.47
CYP2A6 P11509 1/20 0.47
LMNA P02545 3/20 0.46
MAPK1 P28482 2/20 0.46
TRPA1 O75762 2/20 0.46
ALOX5 P09917 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
NFE2L2 Q16236 2/20 0.39
CYP19A1 P11511 1/20 0.39
MAOA P21397 1/20 0.39
ESR1 P03372 1/20 0.39
MAPT P10636 2/20 0.38
RECQL P46063 2/20 0.38
HDAC3 O15379 1/20 0.38
TNKS O95271 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6330351 1.00 MAOB (0.56) MAOBALDH1A1TSHRCYP2A6LMNA
(Z)-1,2-Diphenylethene SCHEMBL817116 0.85 ALDH1A1 (0.53) MAOBALDH1A1TSHRCYP2A6LMNA
SCHEMBL392264 0.84 MAOB (0.72) MAOBALDH1A1LMNAMAPK1TRPA1
SCHEMBL5974265 0.84 MAOB (0.72) MAOBALDH1A1LMNAMAPK1TRPA1
SCHEMBL392263 0.84 MAOB (0.72) MAOBALDH1A1LMNAMAPK1TRPA1
SCHEMBL3654206 0.82 MAOB (0.46) MAOBALDH1A1TSHRCYP2A6LMNA
SCHEMBL7519973 0.82 MAOB (0.46) MAOBALDH1A1TSHRCYP2A6LMNA
SCHEMBL7703499 0.82 MAOB (0.46) MAOBALDH1A1TSHRCYP2A6LMNA
SCHEMBL2657529 0.82 MAOB (0.46) MAOBALDH1A1TSHRCYP2A6LMNA
SCHEMBL3032443 0.82 ALDH1A1 (0.46) MAOBALDH1A1TSHRCYP2A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137748-B Process for preparing polyolefins having one or more pendant functional groups SABIC环球技术有限责任公司 2021-05-04 CN disclosed
CN-108368270-B Process for preparing a polyolefin-based graft copolymer comprising a first functionalized short chain branched polyolefin block and one or more polymer side chains SABIC环球技术有限责任公司 2021-03-02 CN disclosed
CN-108291032-B Process for preparing a polyolefin graft copolymer comprising a first long-chain branched polyolefin block and one or more polymer side chains SABIC环球技术有限责任公司 2021-01-26 CN disclosed
EP-3034545-B1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-11-04 EP disclosed
CN-107223138-B Process for preparing polyolefins having one or more end-functionalized branches SABIC环球技术有限责任公司 2020-10-23 CN disclosed
US-10787545-B2 Process for the preparation of polyolefin-based graft copolymers comprising a first functionalized short chain branched polyolefin block and one or multiple polymer side chains SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-09-29 US disclosed
CN-107531829-B Process for preparing a block copolymer comprising a first polyolefin block and a second polymer block and product obtained from said process SABIC环球技术有限责任公司 2020-09-22 CN disclosed
US-20200262983-A1 PROCESS FOR THE PREPARATION OF POLYOLEFIN-BASED GRAFT COPOLYMERS COMPRISING A FIRST FUNCTIONALIZED SHORT CHAIN BRANCHED POLYOLEFIN BLOCK AND ONE OR MULTIPLE POLYMER SIDE CHAINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-08-20 US disclosed
CN-107207712-B Process for preparing a graft copolymer comprising a polyolefin backbone and one or more polymeric side chains and product obtained from said process SABIC环球技术有限责任公司 2020-08-07 CN disclosed
US-10717826-B2 Process for the preparation of polyolefin-based graft copolymers comprising a first long chain branched polyolefin block and one or multiple polymer side chains SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-07-21 US disclosed
EP-3037438-A1 Process for the preparation of a branched polyolefin SABIC Global Technologies B.V. (NL) 2016-06-29 EP disclosed
EP-3037437-A1 Process for the preparation of a polyolefin having one or multiple end-functionalized branches. SABIC Global Technologies B.V. (NL) 2016-06-29 EP disclosed
EP-3034545-A1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034544-A1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034547-A1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034546-A1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block as well as the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
US-6870017-B2 Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-03-22 US disclosed
US-20030171212-A1 Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-09-11 US disclosed
US-6548686-B2 Coordination catalysts; suppresses heat generation SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-15 US disclosed
US-20020013433-A1 Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020013433-A1 Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer ASH2L, ARL1, AS3MT MAOB 1906/4885ALDH1A1 3244/4885TSHR 4326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.