SCHEMBL6330362

SCHEMBL6330362

CCCCCc1[nH]c2ccccc2c1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OXER1 Q8TDS5 1/20 0.56
RAB9A P51151 1/20 0.55
KDM4E B2RXH2 4/20 0.54
HSD17B10 Q99714 4/20 0.54
ALDH1A1 P00352 3/20 0.54
HPGD P15428 3/20 0.54
GAA P10253 1/20 0.54
CTSV O60911 2/20 0.51
CTSL P07711 2/20 0.51
CYP2D6 P10635 2/20 0.50
AHR P35869 1/20 0.48
CHRNB2 P17787 1/20 0.45
CHRNA7 P36544 1/20 0.45
CHRNA4 P43681 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10082865 0.95 RAB9A (0.57) OXER1RAB9AKDM4EHSD17B10ALDH1A1
SCHEMBL12808068 0.87 RAB9A (0.60) OXER1RAB9AKDM4EHSD17B10ALDH1A1
SCHEMBL8537338 0.87 CYP2D6 (0.66) OXER1RAB9AKDM4EHSD17B10ALDH1A1
SCHEMBL5409935 0.86 CHRNB2 (0.60) OXER1RAB9AKDM4EHSD17B10ALDH1A1
SCHEMBL27921144 0.86 CYP2D6 (0.68) OXER1RAB9AKDM4EHSD17B10ALDH1A1
SCHEMBL17400300 0.86 CYP2D6 (0.68) OXER1RAB9AKDM4EHSD17B10ALDH1A1
SCHEMBL27902363 0.86 CYP2D6 (0.68) OXER1RAB9AKDM4EHSD17B10ALDH1A1
SCHEMBL12891618 0.86 CYP2D6 (0.68) OXER1RAB9AKDM4EHSD17B10ALDH1A1
SCHEMBL28674730 0.85 CHRNB2 (0.59) OXER1RAB9AKDM4EHSD17B10ALDH1A1
SCHEMBL31091563 0.85 CHRNB2 (0.59) OXER1RAB9AKDM4EHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6872835-B2 Process for preparation of fused pyrroles JAPAN SCIENCE & TECHNOLOGY CORPORATION (JP) 2005-03-29 US disclosed
EP-1302459-B1 PROCESSES FOR PREPARATION OF FUSED PYRROLES JAPAN SCIENCE & TECH AGENCY (JP) 2004-10-27 EP disclosed
US-20040049054-A1 Process for preparation of fused pyrroles JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2004-03-11 US disclosed
EP-1302459-A1 PROCESSES FOR PREPARATION OF FUSED PYRROLES Japan Science and Technology Corporation (JP) 2003-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040049054-A1 Process for preparation of fused pyrroles IDO1, IDO2, PAH OXER1 1685/4885RAB9A 1669/4885KDM4E 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.