Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280223 | 0.90 | ADORA2A (0.50) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL5553159 | 0.84 | KMT2A (0.50) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6281252 | 0.84 | ADORA2A (0.46) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6950881 | 0.82 | ADORA2A (0.44) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6325702 | 0.81 | KMT2A (0.42) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL8692415 | 0.81 | KMT2A (0.42) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL8727020 | 0.80 | ALDH1A1 (0.42) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6281244 | 0.79 | ADORA2A (0.50) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL6954140 | 0.78 | ADORA2A (0.42) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 | |
| SCHEMBL5835009 | 0.78 | ADORA2A (0.46) | KMT2AADORA2AADORA1TGFBR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872690-B2 | Herbicidal 2-alkynyl-pyri (mi) dines | WYETH (US) | 2005-03-29 | — | — | US | disclosed |
| EP-0923571-B1 | TRISUBSTITUTED PYRIDINE COMPOUNDS FOR HERBICIDAL USE | BASF AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-20030073581-A1 | Herbicidal 2-alkynyl-pyri (mi) dines | WYETH | 2003-04-17 | — | — | US | disclosed |
| EP-1238586-A1 | Herbicidal 2-alkynyl-pyri(mi)dines | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | disclosed |
| EP-0923571-A2 | TRISUBSTITUTED PYRIDINE COMPOUNDS FOR HERBICIDAL USE | AMERICAN CYANAMID COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998004548-A2 | TRISUBSTITUTED PYRIDINE COMPOUNDS FOR HERBICIDAL USE | AMERICAN CYANAMID COMPANY (US) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073581-A1 | Herbicidal 2-alkynyl-pyri (mi) dines | DDT, AOX1, RIOX2 | KMT2A 1361/4885ADORA2A 2200/4885ADORA1 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.