Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794847 | 0.81 | TDP1 (0.60) | TDP1NPC1HTTALDH1A1KMT2A | |
| SCHEMBL515847 | 0.81 | TDP1 (0.80) | TDP1NPC1HTTALDH1A1KMT2A | |
| SCHEMBL8662502 | 0.80 | TRPV1 (0.52) | TDP1NPC1HTTALDH1A1KMT2A | |
| SCHEMBL9688005 | 0.80 | EPHX2 (0.62) | NPC1HTTSMN1; SMN2TRPV1EPHX2 | |
| SCHEMBL11555162 | 0.80 | TDP1 (0.52) | TDP1NPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10967880 | 0.80 | PPARA (0.56) | TDP1ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL10795425 | 0.79 | TDP1 (0.51) | TDP1NPC1HTTALDH1A1KMT2A | |
| SCHEMBL11553450 | 0.77 | TDP1 (0.46) | TDP1NPC1ALDH1A1KMT2AMAPT | |
| SCHEMBL11681835 | 0.77 | EPHX2 (0.57) | TDP1NPC1ALDH1A1KMT2AMAPT | |
| SCHEMBL22815834 | 0.77 | TRPV1 (0.76) | NPC1HTTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014650-A1 | Delta 1-pyrrolines used as pesticides | BAYER CROPSCIENCE AG (DE) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014650-A1 | Delta 1-pyrrolines used as pesticides | CHRM1, DDT, CHRND | TDP1 562/4885NPC1 4318/4885HTT 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.