Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
| ▸ | GCGR | P47871 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800847 | 0.92 | TDP1 (0.82) | TDP1GCGRRAB9AALDH1A1RORC | |
| SCHEMBL27847099 | 0.89 | TDP1 (0.78) | TDP1GCGRRAB9AALDH1A1RORC | |
| SCHEMBL1567759 | 0.89 | TDP1 (0.64) | TDP1GCGRRAB9AALDH1A1RORC | |
| Triflumuron SCHEMBL23700 | 0.89 | TDP1 (1.00) | TDP1GCGRRAB9AALDH1A1RORC | |
| Triflumuron SCHEMBL29832813 | 0.89 | TDP1 (1.00) | TDP1GCGRRAB9AALDH1A1RORC | |
| Triflumuron SCHEMBL9490691 | 0.89 | TDP1 (1.00) | TDP1GCGRRAB9AALDH1A1RORC | |
| SCHEMBL10710076 | 0.88 | TDP1 (0.77) | TDP1GCGRRAB9AALDH1A1RORC | |
| SCHEMBL7832960 | 0.88 | TDP1 (0.63) | TDP1GCGRRAB9AALDH1A1RORC | |
| SCHEMBL9861823 | 0.87 | TDP1 (0.75) | TDP1GCGRRAB9AALDH1A1RORC | |
| SCHEMBL9327703 | 0.87 | TDP1 (0.95) | TDP1GCGRRAB9AALDH1A1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460408-A1 | Nematicidal compositions | deVGen N.V. (BE) | 2012-06-06 | — | — | EP | claimed |
| EP-0845944-A1 | ACTIVE SUBSTANCE COMBINATIONS COMPRISING PYRETHROIDS AND INSECT-DEVELOPMENT INHIBITORS | BAYER AG (DE) | 1998-06-10 | — | — | EP | claimed |
| WO-1997006687-A1 | ACTIVE SUBSTANCE COMBINATIONS COMPRISING PYRETHROIDS AND INSECT-DEVELOPMENT INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-27 | — | — | WO | claimed |
| EP-0358494-B1 | Emulsifiable concentrate of a pesticide | DOWELANCO (US) | 1994-03-30 | — | — | EP | claimed |
| US-RE32418-E | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1987-05-12 | — | — | US | claimed |
| EP-0124253-A2 | Agricultural compositions, methods of preparing agricultural compositions, and methods of using agricultural compositions | THE DOW CHEMICAL COMPANY (US) | 1984-11-07 | — | — | EP | claimed |
| US-4170657-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1979-10-09 | — | — | US | claimed |
| CN-113784952-B | Esters of non-aromatic heterocyclic compounds having nematicidal activity, their agronomic compositions and uses thereof | 高文作物保护公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-113382996-B | Theophylline derivatives with nematicidal activity, agronomic compositions and related uses | 高文作物保护公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20220204540-A1 | ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2022-06-30 | — | — | US | disclosed |
| US-20220104495-A1 | THEOPHYLLINE DERIVATIVES WITH NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE USE | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2022-04-07 | — | — | US | disclosed |
| EP-3962900-A1 | ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ISAGRO S.p.A. (IT) | 2022-03-09 | — | — | EP | disclosed |
| CN-113784952-A | Esters of non-aromatic heterocyclic compounds with nematicidal activity, their agronomic compositions and uses thereof | 伊萨格罗股份公司 | 2021-12-10 | — | — | CN | disclosed |
| WO-1999016748-A1 | UTILIZING SPIROCYCLIC PHENYL KETO-ENOLS AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-04-08 | — | — | WO | disclosed |
| EP-0358494-B1 | Emulsifiable concentrate of a pesticide | DOWELANCO (US) | 1994-03-30 | — | — | EP | disclosed |
| EP-0124253-B1 | AGRICULTURAL COMPOSITIONS, METHODS OF PREPARING AGRICULTURAL COMPOSITIONS, AND METHODS OF USING AGRICULTURAL COMPOSITIONS | THE DOW CHEMICAL COMPANY (US) | 1990-08-16 | — | — | EP | disclosed |
| EP-0358494-A2 | Emulsifiable concentrate of a pesticide | DOWELANCO (US) | 1990-03-14 | — | — | EP | disclosed |
| US-4529819-A | Method for making benzoylphenylureas | THE DOW CHEMICAL COMPANY (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0124253-A2 | Agricultural compositions, methods of preparing agricultural compositions, and methods of using agricultural compositions | THE DOW CHEMICAL COMPANY (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204540-A1 | ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ACHE, CYP51A1, DNPH1 | TDP1 2793/4885GCGR 3791/4885RAB9A 611/4885 |
| US-20220104495-A1 | THEOPHYLLINE DERIVATIVES WITH NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE USE | ACHE, XDH, TYMP | TDP1 91/4885GCGR 3278/4885RAB9A 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.