Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.62 |
| ▸ | RHOC | P08134 | 1/20 | 0.60 |
| ▸ | RHOA | P61586 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.57 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.56 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.55 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910371 | 0.87 | TRPV1 (0.71) | RHOCRHOARORCENPP3ENPP1 | |
| SCHEMBL4922162 | 0.87 | EPHX2 (0.81) | EPHX2RHOCRHOACNR1RAB9A | |
| SCHEMBL11437835 | 0.83 | HTT (0.58) | NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL10869948 | 0.81 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL6330860 | 0.80 | TDP1 (0.52) | EPHX2ENPP3ENPP1ENPP2TRPV1 | |
| SCHEMBL7599768 | 0.79 | EPHX2 (0.58) | EPHX2RORCTRPV1NPC1RAB9A | |
| SCHEMBL12841602 | 0.79 | RHOC (0.78) | RHOCRHOAENPP3ENPP1ENPP2 | |
| Chlotrifmeuron SCHEMBL10868747 | 0.78 | TDP1 (0.70) | EPHX2RORCPTGS1NPC1RAB9A | |
| SCHEMBL7513604 | 0.78 | TRPV1 (0.83) | EPHX2RORCTRPV1PTGS1NPC1 | |
| SCHEMBL28729179 | 0.78 | EPHX2 (1.00) | EPHX2RORCNPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166180-A | Administering diphenyl substituted (thio)carbonyl(thio)urea derivatives | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-11-24 | — | — | US | disclosed |