Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335744 | 1.00 | ADORA2A (0.43) | ADORA2APIM1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5788569 | 0.92 | ADORA2A (0.52) | ADORA2APIM1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL6331657 | 0.92 | ADORA2A (0.52) | ADORA2APIM1L3MBTL1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6328180 | 0.91 | ADORA2A (0.51) | ADORA2APIM1L3MBTL1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6328189 | 0.91 | ADORA2A (0.51) | ADORA2APIM1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL6330939 | 0.88 | L3MBTL1 (0.46) | PIM1L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL6337475 | 0.88 | L3MBTL1 (0.46) | PIM1L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL6337199 | 0.88 | L3MBTL1 (0.46) | PIM1L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL5802080 | 0.88 | PIM1 (0.41) | PIM1HTR3ASSTR5CAMK1DSSTR2 | |
| SCHEMBL6327624 | 0.88 | PIM1 (0.41) | PIM1HTR3ASSTR5CAMK1DSSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096327-A1 | Novel norepinephrine reuptake inhibitors for the treatment of central nervous system disorders | WARNER-LAMBERT COMPANY LLC | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096327-A1 | Novel norepinephrine reuptake inhibitors for the treatment of central nervous system disorders | SLC6A2, SLC18A2, SLC6A3 | ADORA2A 138/4885PIM1 4198/4885L3MBTL1 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.