SCHEMBL6331065

SCHEMBL6331065

CCCCCCC1=C(Br)/C(=C/Br)OC1=O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 7/20 0.46
CDC25B P30305 7/20 0.46
CDC25C P30307 6/20 0.46
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
GPR84 Q9NQS5 1/20 0.35
ALOX5 P09917 9/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6331066 1.00 CDC25A (0.46) CDC25ACDC25BCDC25CALDH1A1MAPT
Fimbrolide SCHEMBL1049934 0.93 CDC25A (0.38) CDC25ACDC25BCDC25CALOX5
Fimbrolide SCHEMBL13668734 0.93 CDC25A (0.38) CDC25ACDC25BCDC25CALOX5
Fimbrolide SCHEMBL1049932 0.93 CDC25A (0.38) CDC25ACDC25BCDC25CALOX5
SCHEMBL4652230 0.87 CDC25A (0.43) CDC25ACDC25BCDC25CALDH1A1MAPT
SCHEMBL4652165 0.87 CDC25A (0.43) CDC25ACDC25BCDC25CALDH1A1MAPT
SCHEMBL4650435 0.87 CDC25A (0.43) CDC25ACDC25BCDC25CALDH1A1MAPT
SCHEMBL4650432 0.87 CDC25A (0.43) CDC25ACDC25BCDC25CALDH1A1MAPT
SCHEMBL4652232 0.87 CDC25A (0.43) CDC25ACDC25BCDC25CALDH1A1MAPT
SCHEMBL4652162 0.87 CDC25A (0.43) CDC25ACDC25BCDC25CALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050215772-A1 Furanone derivatives and methods of making same BIOSIGNAL LIMITED (AT) 2005-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050215772-A1 Furanone derivatives and methods of making same PFAS, CFAP20, FDPS CDC25A 4351/4885CDC25B 3902/4885CDC25C 4048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.