Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332970 | 1.00 | GPR119 (0.40) | GPR119USP30DPP4JAK2JAK1 | |
| SCHEMBL6332967 | 1.00 | GPR119 (0.40) | GPR119USP30DPP4JAK2JAK1 | |
| SCHEMBL6331203 | 1.00 | GPR119 (0.40) | GPR119USP30DPP4JAK2JAK1 | |
| SCHEMBL6331201 | 1.00 | GPR119 (0.40) | GPR119USP30DPP4JAK2JAK1 | |
| SCHEMBL6333052 | 0.84 | USP30 (0.40) | GPR119USP30TACR1 | |
| SCHEMBL6333049 | 0.84 | USP30 (0.40) | GPR119USP30TACR1 | |
| SCHEMBL6333050 | 0.84 | USP30 (0.40) | GPR119USP30TACR1 | |
| SCHEMBL6333295 | 0.81 | GPR119 (0.39) | GPR119USP30JAK2JAK1TYK2 | |
| SCHEMBL6333294 | 0.81 | GPR119 (0.39) | GPR119USP30JAK2JAK1TYK2 | |
| SCHEMBL6333298 | 0.81 | GPR119 (0.39) | GPR119USP30JAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881733-B1 | Serotonergic benzofurans | ELI LILLY AND COMPANY (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1204659-B1 | SEROTONERGIC BENZOFURANS | LILLY CO ELI (US) | 2003-11-26 | — | — | EP | disclosed |
| EP-1204659-A2 | SEROTONERGIC BENZOFURANS | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009122-A2 | SEROTONERGIC BENZOFURANS | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |