Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197726 | 0.83 | CHRM2 (0.52) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL632041 | 0.78 | CHRM2 (0.47) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL631921 | 0.76 | CHRM2 (0.45) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| Ether SCHEMBL17606594 | 0.76 | CHRM2 (0.45) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL632678 | 0.73 | CHRM2 (0.42) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL19943508 | 0.73 | CHRM2 (0.42) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL31263367 | 0.73 | CHRM2 (0.42) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL254883 | 0.73 | — | — | |
| SCHEMBL10025528 | 0.73 | CHRM2 (0.50) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL20599781 | 0.72 | CHRM2 (0.41) | CHRM2MEN1KMT2ACHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197862-B1 | 5-SUBSTITUTED 2-METHYLFURAN | FURANIX TECHNOLOGIES BV (NL) | 2012-02-22 | — | — | EP | claimed |
| US-20100212218-A1 | 5-(SUBSTITUTED METHYL) 2-METHYLFURAN | FURANIX TECHNOLOGIES B.V. (NL) | 2010-08-26 | — | — | US | claimed |
| EP-2197862-A2 | 5-SUBSTITUTED 2-METHYLFURAN | Furanix Technologies B.V (NL) | 2010-06-23 | — | — | EP | claimed |
| WO-2009030510-A2 | 5-(SUBSTITUTED METHYL) 2-METHYLFURAN | FURANIX TECHNOLOGIES B.V. (NL) | 2009-03-12 | — | — | WO | claimed |