Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197726 | 0.83 | CHRM2 (0.52) | CHRM2MEN1CHRM4CHRM5CHRM1 | |
| SCHEMBL12417813 | 0.81 | ALOX5 (0.41) | MAPTPOLBKDM4EALOX5NPC1 | |
| SCHEMBL632041 | 0.78 | CHRM2 (0.47) | CHRM2MEN1CHRM4CHRM5CHRM1 | |
| Ether SCHEMBL17606594 | 0.76 | CHRM2 (0.45) | CHRM2MEN1CHRM4CHRM5CHRM1 | |
| SCHEMBL1664017 | 0.75 | ALDH1A1 (0.49) | MAPTPOLBTDP1TP53KDM4E | |
| SCHEMBL19943508 | 0.73 | CHRM2 (0.42) | CHRM2MEN1CHRM4CHRM5CHRM1 | |
| SCHEMBL633130 | 0.73 | CHRM2 (0.42) | CHRM2MEN1CHRM4CHRM5CHRM1 | |
| SCHEMBL104309 | 0.73 | CHRM2 (0.50) | CHRM2MEN1CHRM4CHRM5CHRM1 | |
| SCHEMBL254883 | 0.73 | — | — | |
| SCHEMBL10976512 | 0.72 | HSD17B10 (0.40) | KMT2APOLBTDP1KDM4EALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197862-B1 | 5-SUBSTITUTED 2-METHYLFURAN | FURANIX TECHNOLOGIES BV (NL) | 2012-02-22 | — | — | EP | claimed |
| US-20100212218-A1 | 5-(SUBSTITUTED METHYL) 2-METHYLFURAN | FURANIX TECHNOLOGIES B.V. (NL) | 2010-08-26 | — | — | US | claimed |
| EP-2197862-A2 | 5-SUBSTITUTED 2-METHYLFURAN | Furanix Technologies B.V (NL) | 2010-06-23 | — | — | EP | claimed |
| WO-2009030510-A2 | 5-(SUBSTITUTED METHYL) 2-METHYLFURAN | FURANIX TECHNOLOGIES B.V. (NL) | 2009-03-12 | — | — | WO | claimed |
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | CHRM2 4005/4885MEN1 4773/4885CHRM4 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.