Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | PPM1A | P35813 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335121 | 0.94 | NPC1 (0.38) | NPC1RAB9AACHEMAPTPPM1A | |
| SCHEMBL4624927 | 0.82 | CHKA (0.40) | — | |
| SCHEMBL4625719 | 0.76 | KDM4E (0.41) | NPC1RAB9AACHEMAPTPOLB | |
| SCHEMBL6743884 | 0.71 | CHKA (0.39) | — | |
| SCHEMBL4625936 | 0.69 | KDM4E (0.44) | NPC1RAB9AMAPTPOLBKDM4E | |
| SCHEMBL6334825 | 0.69 | PTGER4 (0.38) | NPC1RAB9AMAPTPOLBKDM4E | |
| SCHEMBL6333892 | 0.68 | HSD17B10 (0.44) | MAPTPOLBKDM4EALDH1A1LMNA | |
| SCHEMBL6340569 | 0.67 | KDM4E (0.39) | MAPTKDM4EHSD17B10 | |
| SCHEMBL6333065 | 0.67 | HSD17B10 (0.40) | ACHEMAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL6744503 | 0.66 | HSD17B10 (0.39) | MAPTPOLBKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6977001-B2 | Dye compositions containing quinolinium salts | WELLA AG (DE) | 2005-12-20 | — | — | US | claimed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | claimed |
| US-20030177592-A1 | Dye compositions containing quinolinium salts | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-09-25 | — | — | US | claimed |
| EP-1346719-A1 | Dyeing compositions containing quinolinium salts | Wella Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | claimed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | claimed |
| US-6977001-B2 | Dye compositions containing quinolinium salts | WELLA AG (DE) | 2005-12-20 | — | — | US | disclosed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | disclosed |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | disclosed |
| US-20030177592-A1 | Dye compositions containing quinolinium salts | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-09-25 | — | — | US | disclosed |
| EP-1346719-A1 | Dyeing compositions containing quinolinium salts | Wella Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | KRT18, COL2A1, PHB1 | NPC1 4709/4885RAB9A 4719/4885ACHE 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.