SCHEMBL6334304

SCHEMBL6334304

O=C(O)c1cccc(-n2cnc(-c3nc(C4CCCCC4)[nH]c3COC34CC5CC(CC(C5)C3)C4)n2)c1

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 2/20 0.60
PTGER1 P34995 5/20 0.34
KMO O15229 1/20 0.33
CCKAR P32238 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6334312 0.91 CCKBR (0.49) CCKBR
SCHEMBL6334704 0.79 CCKBR (0.61) CCKBR
SCHEMBL7041889 0.79 CCKBR (0.43) CCKBRPTGER1KMOCCKAR
SCHEMBL6339248 0.78 CCKBR (0.61) CCKBR
SCHEMBL6334684 0.78 CCKBR (0.61) CCKBRKMO
SCHEMBL6334315 0.77 CCKBR (0.60) CCKBR
SCHEMBL6334200 0.77 CCKBR (0.60) CCKBRKMO
SCHEMBL6338529 0.76 CCKBR (0.59) CCKBRKMOCCKAR
SCHEMBL6332353 0.76 CCKBR (0.59) CCKBRKMOCCKAR
SCHEMBL6094542 0.76 CCKBR (0.58) CCKBRKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6878734-B2 Gastrin and cholecystokinin receptor ligands(II) JAMES BLACK FOUNDATION LIMITED (GB) 2005-04-12 US disclosed
US-20030199565-A1 Gastrin and cholecystokinin receptor ligands(II) JAMES BLACK FOUNDATION LIMITED (GB) 2003-10-23 US disclosed
WO-2001085723-A1 GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS (II) JAMES BLACK FOUNDATION LIMITED (GB) 2001-11-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199565-A1 Gastrin and cholecystokinin receptor ligands(II) GRPR, CCKBR, GIPR CCKBR 2/4885PTGER1 73/4885KMO 3972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.