Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332094 | 0.91 | CCKBR (0.53) | CCKBRNR1H4PDE4DPDE7A | |
| SCHEMBL6334315 | 0.88 | CCKBR (0.60) | CCKBRNR1H4 | |
| SCHEMBL6339248 | 0.85 | CCKBR (0.61) | CCKBRNR1H4 | |
| SCHEMBL6334704 | 0.84 | CCKBR (0.61) | CCKBRNR1H4 | |
| SCHEMBL6334200 | 0.83 | CCKBR (0.60) | CCKBRNR1H4KMO | |
| SCHEMBL6333921 | 0.80 | CCKBR (0.52) | CCKBRNR1H4PDE4DPDE7A | |
| SCHEMBL6334304 | 0.78 | CCKBR (0.60) | CCKBRKMO | |
| SCHEMBL6332352 | 0.77 | CCKBR (0.59) | CCKBRNR1H4KMO | |
| SCHEMBL6338529 | 0.77 | CCKBR (0.59) | CCKBRKMO | |
| SCHEMBL6332091 | 0.77 | CCKBR (0.53) | CCKBRNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878734-B2 | Gastrin and cholecystokinin receptor ligands(II) | JAMES BLACK FOUNDATION LIMITED (GB) | 2005-04-12 | — | — | US | disclosed |
| US-20030199565-A1 | Gastrin and cholecystokinin receptor ligands(II) | JAMES BLACK FOUNDATION LIMITED (GB) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199565-A1 | Gastrin and cholecystokinin receptor ligands(II) | GRPR, CCKBR, GIPR | CCKBR 2/4885NR1H4 79/4885PDE4D 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.