Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 4/20 | 0.31 |
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.31 |
| ▸ | SLC6A2 known ✓ | P23975 | 4/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 4/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.31 |
| ▸ | DRD3 | P35462 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.31 |
| ▸ | DRD1 | P21728 | 3/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6332725 | 0.84 | ADRA2A (0.31) | IDO1TDO2CHRNA7CYP2D6CHRM2 | |
| Hydrochloric Acid SCHEMBL6334516 | 0.84 | IDO1 (0.30) | IDO1TDO2CHRNA7CYP2D6CHRM2 | |
| Hydrochloric Acid SCHEMBL6334282 | 0.83 | IDO1 (0.30) | IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL6332556 | 0.83 | HTT (0.35) | NPSR1SMN1; SMN2CHRNA7CYP2D6CHRM2 | |
| Hydrochloric Acid SCHEMBL6332224 | 0.81 | HTT (0.39) | NPSR1SMN1; SMN2CHRNA7CYP2D6CHRM2 | |
| Hydrochloric Acid SCHEMBL6332903 | 0.79 | HTT (0.38) | NPSR1SMN1; SMN2CHRNA7CYP2D6CHRM2 | |
| Hydrochloric Acid SCHEMBL6337018 | 0.74 | TAAR1 (0.33) | CYP2D6SLC6A2SLC6A3SLC6A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL6337022 | 0.71 | ABCB1 (0.30) | HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL6334559 | 0.70 | ABCB1 (0.34) | IDO1TDO2CYP2D6SLC6A2SLC6A3 | |
| SCHEMBL461448 | 0.70 | IDO1 (0.47) | IDO1TDO2NPSR1SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6870017-B2 | Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-03-22 | — | — | US | disclosed |
| US-20030171212-A1 | Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-09-11 | — | — | US | disclosed |
| US-6548686-B2 | Coordination catalysts; suppresses heat generation | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-04-15 | — | — | US | disclosed |
| US-20020013433-A1 | Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013433-A1 | Transition metal compound, catalyst for addition polymerization, and process for producing addition polymer | ASH2L, ARL1, AS3MT | CHRM2 3776/4885CHRM1 2478/4885SLC6A2 4111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.