SCHEMBL6334545

SCHEMBL6334545

COC(=O)C(=O)OC1CCCC(C)(C)C1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 5/20 0.36
EPHX1 P07099 2/20 0.32
NPSR1 Q6W5P4 1/20 0.31
MAPT P10636 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6335395 0.84 SCN9A (0.37) SCN9AEPHX1NPSR1MAPTCYP2C19
SCHEMBL6327731 0.82 SCN9A (0.32) SCN9A
SCHEMBL6325837 0.82 PTPN2 (0.35) SCN9AEPHX1MAPTCYP2C19
SCHEMBL23494257 0.81 SCN9A (0.33) SCN9A
SCHEMBL13195791 0.80 SCN9A (0.36) SCN9AEPHX1CYP2C19
SCHEMBL6334628 0.80 CYP2C19 (0.38) SCN9AEPHX1CYP2C19
SCHEMBL6325221 0.80 NAAA (0.33) SCN9AEPHX1
SCHEMBL27774495 0.79 ATM (0.38) SCN9AEPHX1CYP2C19
SCHEMBL3051316 0.79 ATM (0.38) SCN9AEPHX1CYP2C19
SCHEMBL28168096 0.77 EPHX1 (0.44) EPHX1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919477-B2 Fruity musk compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2005-07-19 US disclosed
US-6774260-B2 ALKYL 1-(3,3-DIMETHYLCYCLOHEXYL) ETHYL MALONATE DERIVATIVES; SOAPS, COSMETICS, PERFUMES, CLEANING COMPOUNDS, DETERGENTS; MUSKY ODOR INTERNATIONAL FLAVORS & FRAGRANCES INC. 2004-08-10 US disclosed
EP-1398366-A1 Fruity musk compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2004-03-17 EP disclosed