SCHEMBL6325221

SCHEMBL6325221

CCCOC(=O)C(=O)OC1CCCC(C)(C)C1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.33
SCN9A Q15858 2/20 0.31
EPHX1 P07099 1/20 0.31
PPM1B O75688 1/20 0.31
PTPN1 P18031 1/20 0.31
PPP1CC P36873 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6325837 0.88 PTPN2 (0.35) NAAASCN9AEPHX1PTPN1
SCHEMBL6330192 0.87 NAAA (0.33) NAAASCN9AEPHX1PPM1BPTPN1
SCHEMBL6332696 0.83 NAAA (0.37) NAAASCN9AEPHX1PPM1BPTPN1
SCHEMBL6334545 0.80 SCN9A (0.36) SCN9AEPHX1
SCHEMBL6337110 0.77 ALDH1A1 (0.38) NAAASCN9AEPHX1
SCHEMBL28208008 0.77 NAAA (0.49) NAAASCN9AEPHX1
SCHEMBL2452485 0.76 NAAA (0.40) NAAASCN9AEPHX1
SCHEMBL19830971 0.76 NAAA (0.40) NAAASCN9AEPHX1
SCHEMBL28369306 0.76 EPHX1 (0.33) NAAASCN9AEPHX1
SCHEMBL6327731 0.76 SCN9A (0.32) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919477-B2 Fruity musk compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2005-07-19 US disclosed
US-6774260-B2 ALKYL 1-(3,3-DIMETHYLCYCLOHEXYL) ETHYL MALONATE DERIVATIVES; SOAPS, COSMETICS, PERFUMES, CLEANING COMPOUNDS, DETERGENTS; MUSKY ODOR INTERNATIONAL FLAVORS & FRAGRANCES INC. 2004-08-10 US disclosed
EP-1398366-A1 Fruity musk compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2004-03-17 EP disclosed