SCHEMBL633469

SCHEMBL633469

COc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 6/20 1.00
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
CYP3A4 P08684 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
TP53 P04637 3/20 1.00
MAPT P10636 3/20 1.00
HPGD P15428 3/20 1.00
ALOX15 P16050 3/20 1.00
MAPK1 P28482 3/20 1.00
ALDH1A1 P00352 2/20 1.00
ALOX12 P18054 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
NFKB1 P19838 4/20 0.85
NFKB2 Q00653 3/20 0.85
RELA Q04206 3/20 0.85
FLT3 P36888 2/20 0.83
CTSL P07711 2/20 0.79
MAOB P27338 3/20 0.74
ACHE P22303 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL633470 1.00 ABCG2 (1.00) ABCG2MEN1KMT2ACYP3A4TDP1
SCHEMBL30383806 1.00 ABCG2 (1.00) ABCG2MEN1KMT2ACYP3A4TDP1
SCHEMBL25217986 1.00 ABCG2 (1.00) ABCG2MEN1KMT2ACYP3A4TDP1
Ethane SCHEMBL25195312 0.99 ABCG2 (0.97) ABCG2MEN1KMT2ACYP3A4TDP1
Homobutein SCHEMBL633521 0.92 MEN1 (1.00) ABCG2MEN1KMT2ACYP3A4TDP1
SCHEMBL25206351 0.92 MEN1 (0.85) ABCG2MEN1KMT2ACYP3A4TDP1
Homobutein SCHEMBL25190880 0.92 MEN1 (1.00) ABCG2MEN1KMT2ACYP3A4TDP1
SCHEMBL633170 0.92 MEN1 (0.85) ABCG2MEN1KMT2ACYP3A4TDP1
Homobutein SCHEMBL31028350 0.92 MEN1 (1.00) ABCG2MEN1KMT2ACYP3A4TDP1
Homobutein SCHEMBL633522 0.92 MEN1 (1.00) ABCG2MEN1KMT2ACYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 EP claimed
WO-2024156359-A1 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 WO claimed
WO-2024156879-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 WO claimed
EP-1888174-B1 USE OF CHALCONES FOR THE TREATMENT OF VIRAL DISORDERS JOHNSON & JOHNSON CONSUMER (US) 2012-02-22 EP claimed
EP-1888174-A1 USE OF CHALCONES FOR THE TREATMENT OF VIRAL DISORDERS Johnson and Johnson Consumer Companies, Inc. (US) 2008-02-20 EP claimed
WO-2006127539-A1 USE OF CHALCONES FOR THE TREATMENT OF VIRAL DISORDERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2006-11-30 WO claimed
US-20060270614-A1 Use of chalcones for the treatment of viral disorders JOHNSON & JOHNSON CONSUMER COMPANIES, INC. 2006-11-30 US claimed
WO-1995006628-A1 TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA STATENS SERUMINSTITUT (DK) 1995-03-09 WO claimed
EP-4747367-A1 NEW ENZYMES FOR THE MANUFACTURING OF 4'-O-METHYLATED PHENOLIC SUBSTANCES Symrise AG (DE) 2026-05-27 EP disclosed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 EP disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2025017042-A1 NEW ENZYMES FOR THE MANUFACTURING OF 4'-O-METHYLATED PHENOLIC SUBSTANCES SYMRISE AG (DE) 2025-01-23 WO disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
WO-2006127539-A1 USE OF CHALCONES FOR THE TREATMENT OF VIRAL DISORDERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2006-11-30 WO disclosed
US-20060270614-A1 Use of chalcones for the treatment of viral disorders JOHNSON & JOHNSON CONSUMER COMPANIES, INC. 2006-11-30 US disclosed
US-20060135445-A1 Breast cancer-resistant protein inhibitor KABUSHIKI KAISHA YAKULT HONSHA (JP) 2006-06-22 US disclosed
WO-2005117849-A1 DIARYLALKANES AS POTENT INHIBITORS OF BINUCLEAR ENZYMES UNIGEN PHARMACEUTICALS, INC. (US) 2005-12-15 WO disclosed
US-20050267047-A1 Diarylalkanes as potent inhibitors of binuclear enzymes UNIGEN PHARMACEUTICALS, INC. (US) 2005-12-01 US disclosed
EP-1591112-A1 BREAST CANCER-RESISTANT PROTEIN INHIBITOR Kabushiki Kaisha Yakult Honsha (JP) 2005-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050267047-A1 Diarylalkanes as potent inhibitors of binuclear enzymes TYR, DDT, HAAO ABCG2 1756/4885MEN1 2314/4885KMT2A 2846/4885
US-20060135445-A1 Breast cancer-resistant protein inhibitor ABCC1, BCR, BRCA1 ABCG2 8/4885MEN1 4488/4885KMT2A 2476/4885
US-20060270614-A1 Use of chalcones for the treatment of viral disorders HAVCR2, HMGB3, EIF2AK2 ABCG2 3800/4885MEN1 3326/4885KMT2A 4014/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MEN1 3367/4885KMT2A 2792/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MEN1 2457/4885KMT2A 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.