Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406009 | 1.00 | THRB (0.31) | THRBALOX15 | |
| SCHEMBL8413548 | 0.71 | — | — | |
| SCHEMBL15193066 | 0.68 | THRB (0.32) | THRBALOX15 | |
| SCHEMBL8412576 | 0.68 | THRB (0.32) | THRBALOX15 | |
| SCHEMBL6411507 | 0.68 | — | — | |
| SCHEMBL6411494 | 0.68 | — | — | |
| SCHEMBL5552553 | 0.66 | — | — | |
| SCHEMBL7623270 | 0.66 | — | — | |
| SCHEMBL11970800 | 0.65 | — | — | |
| SCHEMBL17309909 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919465-B2 | Method of preparing (3R, 3aS, 6aR)-3-hydroxyhexahydrofuro[2,3,-b] furan and related compounds | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-07-19 | — | — | US | disclosed |
| US-20040127727-A1 | Method of preparing (3R, 3aS, 6aR) -3-hydroxyhexahydrofuro [2,3,-b] furan and related compounds | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127727-A1 | Method of preparing (3R, 3aS, 6aR) -3-hydroxyhexahydrofuro [2,3,-b] furan and related compounds | HSD3B1, HSD3B2, CYP1B1 | THRB 2817/4885ALOX15 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.