SCHEMBL633557

SCHEMBL633557

Cc1ccc2nc(-c3ccc(N)cc3)sc2c1S(=O)(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 1.00
ALDH1A1 P00352 5/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
GLA P06280 4/20 1.00
HPGD P15428 4/20 1.00
TP53 P04637 3/20 1.00
RECQL P46063 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
HSD17B10 Q99714 2/20 1.00
CYP3A4 P08684 1/20 1.00
NT5E P21589 1/20 1.00
CASP1 P29466 1/20 1.00
CASP7 P55210 1/20 1.00
MAPT P10636 8/20 0.55
APP P05067 8/20 0.55
SNCA P37840 1/20 0.55
KDM4E B2RXH2 5/20 0.50
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
POLB P06746 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL28754258 0.97 GAA (0.95) GAAALDH1A1SMN1; SMN2GLAHPGD
SCHEMBL15939945 0.94 GAA (0.88) GAAALDH1A1SMN1; SMN2GLAHPGD
SCHEMBL14768668 0.93 GAA (0.86) GAAALDH1A1SMN1; SMN2GLAHPGD
SCHEMBL5578358 0.93 GAA (0.86) GAAALDH1A1SMN1; SMN2GLAHPGD
SCHEMBL15940004 0.93 GAA (0.86) GAAALDH1A1SMN1; SMN2GLAHPGD
SCHEMBL10605029 0.93 GAA (0.86) GAAALDH1A1SMN1; SMN2GLAHPGD
SCHEMBL15093377 0.92 GAA (0.84) GAAALDH1A1SMN1; SMN2GLAHPGD
SCHEMBL9612305 0.89 GAA (0.81) GAAALDH1A1SMN1; SMN2GLAHPGD
SCHEMBL14768734 0.87 ALDH1A1 (0.76) GAAALDH1A1SMN1; SMN2GLAHPGD
SCHEMBL1456224 0.87 GAA (0.77) GAAALDH1A1SMN1; SMN2GLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10392514-B2 Storage-stable dye solutions ARCHROMA IP GMBH (CH) 2019-08-27 US claimed
EP-3122820-B1 STORAGE-STABLE DYE SOLUTIONS ARCHROMA IP GMBH (CH) 2019-03-13 EP claimed
CN-106459600-B The dye solution of stable storage 昂高知识产权有限公司 2018-09-21 CN claimed
CN-106459600-A Storage-stable dye solutions 昂高知识产权有限公司 2017-02-22 CN claimed
EP-3122820-A1 STORAGE-STABLE DYE SOLUTIONS Archroma IP GmbH (CH) 2017-02-01 EP claimed
US-20170022366-A1 STORAGE-STABLE DYE SOLUTIONS ARCHROMA IP GMBH (CH) 2017-01-26 US claimed
WO-2015144315-A1 STORAGE-STABLE DYE SOLUTIONS ARCHROMA IP GMBH (CH) 2015-10-01 WO claimed
US-8900414-B2 Fiber products DATALASE, LTD. (GB) 2014-12-02 US claimed
EP-2207933-B1 NEW FIBER PRODUCTS DATALASE LTD (GB) 2014-05-21 EP claimed
CN-102863819-A Dye solution for textile printing and dyeing WUXI XINDE DYEING PRINTING PRODUCT CO LTD 2013-01-09 CN claimed
WO-1999058013-A1 RE-FORMATION OF KERATINOUS FIBRE CROSS LINKS NOVO NORDISK A/S (DK) 1999-11-18 WO claimed
US-5951714-A Enzymatic discharge printing of dyed textiles NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) 1999-09-14 US claimed
US-5899212-A CLEAVAGE OF DISULFIDE BONDS, OXIDOREDUCTASE NOVO NORDISK A/S (DK) 1999-05-04 US claimed
WO-1998046820-A1 ENZYMATIC DISCHARGE PRINTING OF DYED TEXTILES NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) 1998-10-22 WO claimed
CN-1126490-A Enhancement of laccase reactions NOVO NORDISK AS (DK) 1996-07-10 CN claimed
EP-0707637-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1996-04-24 EP claimed
EP-0679183-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK A/S (DK) 1995-11-02 EP claimed
WO-1995001426-A1 ENHANCEMENT OF LACCASE REACTIONS NOVO NORDISK A/S (DK) 1995-01-12 WO claimed
WO-1994012621-A1 ENHANCEMENT OF ENZYME REACTIONS NOVO NORDISK (DK) 1994-06-09 WO claimed
EP-0072481-A1 Tamperproof paper BAYER AG (DE) 1983-02-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392514-B2 Storage-stable dye solutions IK, G6PD, TYR GAA 243/4885ALDH1A1 59/4885SMN1; SMN2 1686/4885
US-20170022366-A1 STORAGE-STABLE DYE SOLUTIONS IK, G6PD, TYR GAA 243/4885ALDH1A1 59/4885SMN1; SMN2 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.