SCHEMBL6336282

SCHEMBL6336282

CC(Cl)c1ccc2c(c1)OC(F)(F)O2

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GPR55 Q9Y2T6 1/20 0.43
PDE2A O00408 9/20 0.41
OGA O60502 2/20 0.39
CTNNB1 P35222 1/20 0.36
WNT3A P56704 1/20 0.36
ACACB O00763 2/20 0.36
NOTUM Q6P988 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CG P48736 1/20 0.36
KIF11 P52732 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMYD3 Q9H7B4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8744987 0.85 GPR55 (0.39) GPR55PDE2AOGACTNNB1WNT3A
SCHEMBL879006 0.85 GPR55 (0.45) GPR55PDE2AOGACTNNB1WNT3A
SCHEMBL24509831 0.83 TSHR (0.48) GPR55KIF11NPC1RAB9A
SCHEMBL3669583 0.81 GPR55 (0.43) GPR55PDE2AOGACTNNB1WNT3A
SCHEMBL20559520 0.81 GPR55 (0.43) GPR55PDE2AOGACTNNB1WNT3A
SCHEMBL26923716 0.81 PDE2A (0.44) GPR55PDE2AOGACTNNB1WNT3A
SCHEMBL24494541 0.81 GPR55 (0.43) GPR55PDE2AOGACTNNB1WNT3A
SCHEMBL17541572 0.81 PDE2A (0.44) GPR55PDE2AOGACTNNB1WNT3A
SCHEMBL30687097 0.81 PDE2A (0.44) GPR55PDE2AOGACTNNB1WNT3A
SCHEMBL26938923 0.81 PDE2A (0.44) GPR55PDE2AOGACTNNB1WNT3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326749-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF SIONNA THERAPEUTICS INC (US) 2025-10-23 US disclosed
EP-4536655-A2 COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF Sionna Therapeutics Inc. (US) 2025-04-16 EP disclosed
CN-119677730-A Compounds, compositions, and methods of use thereof 希安纳医疗公司 2025-03-21 CN disclosed
US-12187741-B2 Glycosidase inhibitors ASCENEURON SA (CH) 2025-01-07 US disclosed
WO-2023240267-A2 COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF SIONNA THERAPEUTICS (US) 2023-12-14 WO disclosed
WO-2023240267-A2 COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF SIONNA THERAPEUTICS (US) 2023-12-14 WO disclosed
US-20220411440-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-12-29 US disclosed
US-20220411440-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-12-29 US disclosed
CN-107108601-B Glycosidase inhibitors 阿森纽荣股份公司 2021-08-20 CN disclosed
EP-3186243-B1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2021-07-21 EP disclosed
US-11046712-B2 Glycosidase inhibitors ASCENEURON SA (CH) 2021-06-29 US disclosed
US-10336775-B2 Glycosidase inhibitors ASCENEURON SA (CH) 2019-07-02 US disclosed
US-10336775-B2 Glycosidase inhibitors ASCENEURON SA (CH) 2019-07-02 US disclosed
US-20170298082-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2017-10-19 US disclosed
US-20170298082-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2017-10-19 US disclosed
US-20170298082-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2017-10-19 US disclosed
EP-3186243-A1 GLYCOSIDASE INHIBITORS Asceneuron SA (CH) 2017-07-05 EP disclosed
WO-2016030443-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2016-03-03 WO disclosed
WO-2016030443-A1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2016-03-03 WO disclosed
US-20050209274-A1 Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor ABOTT LABORATORIES 2005-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411440-A1 GLYCOSIDASE INHIBITORS GAA, ENGASE, GBA3 GPR55 3664/4885PDE2A 1719/4885OGA 77/4885
US-20250326749-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF CFTR, SLC26A4, PKD2 GPR55 1983/4885PDE2A 94/4885OGA 2605/4885
US-12187741-B2 Glycosidase inhibitors GAA, ENGASE, GBA3 GPR55 3664/4885PDE2A 1719/4885OGA 77/4885
US-20170298082-A1 GLYCOSIDASE INHIBITORS GAA, ENGASE, GBA3 GPR55 3664/4885PDE2A 1719/4885OGA 77/4885
US-10336775-B2 Glycosidase inhibitors GAA, ENGASE, GBA3 GPR55 3664/4885PDE2A 1719/4885OGA 77/4885
US-20050209274-A1 Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor MCHR1, MCHR2, MC1R GPR55 496/4885PDE2A 1344/4885OGA 3859/4885
US-11046712-B2 Glycosidase inhibitors GAA, ENGASE, GBA3 GPR55 3664/4885PDE2A 1719/4885OGA 77/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.