SCHEMBL6337027

SCHEMBL6337027

CON(C)C(=O)c1ccc(Oc2ccc(OCc3ccccc3)cc2)nc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACACB O00763 3/20 0.50
ACACA Q13085 3/20 0.50
OPRM1 P35372 3/20 0.50
OPRD1 P41143 3/20 0.50
OPRK1 P41145 2/20 0.50
MAOB P27338 1/20 0.50
EGFR P00533 4/20 0.49
MEN1 O00255 1/20 0.49
PABPC1 P11940 1/20 0.49
KMT2A Q03164 1/20 0.49
NR4A1 P22736 1/20 0.49
NR4A2 P43354 1/20 0.49
NR4A3 Q92570 1/20 0.49
PARP10 Q53GL7 1/20 0.47
ALOX5 P09917 2/20 0.46
SRD5A2 P31213 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31081572 0.88 CXCR2 (0.50) MAOBEGFRMEN1PABPC1KMT2A
SCHEMBL6348703 0.87 PPARG (0.42) OPRM1OPRD1OPRK1MAOBEGFR
SCHEMBL6338944 0.87 FFAR4 (0.43) OPRM1OPRD1OPRK1KMT2A
SCHEMBL1034311 0.85 MAOB (0.63) MAOBEGFRMEN1KMT2ANR4A1
SCHEMBL6339006 0.83 OPRM1 (0.57) ACACBACACAOPRM1OPRD1OPRK1
SCHEMBL6346472 0.83 MAOB (0.69) ACACBACACAOPRM1OPRD1OPRK1
SCHEMBL6339254 0.83 NR4A2 (0.68) ACACBACACAOPRM1OPRD1OPRK1
SCHEMBL6703917 0.82 NR4A2 (0.70) MAOBEGFRNR4A1NR4A2NR4A3
SCHEMBL6350325 0.81 MAOB (0.47) MAOBEGFRNR4A1NR4A2NR4A3
SCHEMBL6347635 0.77 MAOB (0.59) ACACBACACAOPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 ACACB 1367/4885ACACA 1115/4885OPRM1 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.