SCHEMBL6350325

SCHEMBL6350325

CON(C)C(=O)c1ccc(Sc2ccc(OCc3ccccc3)cc2)nc1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.47
EGFR P00533 5/20 0.46
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
PARP10 Q53GL7 1/20 0.44
ALOX5 P09917 2/20 0.44
SRD5A2 P31213 1/20 0.43
PLA2G4B P0C869 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6339246 0.84 MAOB (0.51) MAOBNR4A1NR4A2NR4A3PARP10
SCHEMBL6347648 0.84 MAOB (0.64) MAOBEGFRNR4A1NR4A2NR4A3
SCHEMBL6341711 0.84 NR4A2 (0.62) MAOBNR4A1NR4A2NR4A3PARP10
SCHEMBL1034311 0.83 MAOB (0.63) MAOBEGFRNR4A1NR4A2NR4A3
SCHEMBL6337027 0.81 ACACB (0.50) MAOBEGFRNR4A1NR4A2NR4A3
SCHEMBL6703917 0.79 NR4A2 (0.70) MAOBEGFRNR4A1NR4A2NR4A3
SCHEMBL31081572 0.78 CXCR2 (0.50) MAOBEGFR
SCHEMBL6347392 0.76 FFAR1 (0.50) MAOBNR4A1NR4A2NR4A3PARP10
SCHEMBL20103340 0.74 KMT2A (0.49) MAOBNR4A2
SCHEMBL6348703 0.73 PPARG (0.42) MAOBEGFRNR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890932-B2 Immunoglobulin e antibody suppressors TEIJIN LIMITED (JP) 2005-05-10 US disclosed
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed
US-20030232811-A1 Immunoglobulin e antibody suppressors TEIJIN LIMITED 2003-12-18 US disclosed
US-6649656-B1 Anticarcinogenic, antiallergen, antishock, and antiasthmatic agents TEIJIN LIMITED (JP) 2003-11-18 US disclosed
EP-1101755-A1 ANTHRANILIC ACID DERIVATIVES TEIJIN LIMITED (JP) 2001-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030232811-A1 Immunoglobulin e antibody suppressors IGLV6-57, FCGRT, IGSF11 MAOB 2681/4885EGFR 1011/4885NR4A1 1697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.