Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.94 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | LAP3 | P28838 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294046 | 1.00 | OPRM1 (0.94) | OPRM1TP53SPHK1CYP2D6LMNA | |
| SCHEMBL2365616 | 1.00 | OPRM1 (0.94) | OPRM1TP53SPHK1CYP2D6LMNA | |
| SCHEMBL16366968 | 1.00 | OPRM1 (0.94) | OPRM1TP53SPHK1CYP2D6LMNA | |
| SCHEMBL37106 | 1.00 | OPRM1 (0.94) | OPRM1TP53SPHK1CYP2D6LMNA | |
| SCHEMBL20495958 | 1.00 | OPRM1 (0.94) | OPRM1TP53SPHK1CYP2D6LMNA | |
| SCHEMBL20495969 | 1.00 | OPRM1 (0.94) | OPRM1TP53SPHK1CYP2D6LMNA | |
| SCHEMBL20495963 | 1.00 | OPRM1 (0.94) | OPRM1TP53SPHK1CYP2D6LMNA | |
| SCHEMBL20495967 | 1.00 | OPRM1 (0.94) | OPRM1TP53SPHK1CYP2D6LMNA | |
| SCHEMBL20495961 | 1.00 | OPRM1 (0.94) | OPRM1TP53SPHK1CYP2D6LMNA | |
| SCHEMBL20820762 | 1.00 | OPRM1 (0.94) | OPRM1TP53SPHK1CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189053-B1 | AN IMPROVED PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | UNICHEM LAB LTD (IN) | 2021-05-05 | — | — | EP | claimed |
| EP-3617243-A1 | METHOD FOR THE PRODUCTION OF POLYISOCYANATES COMPRISING ISOCYANURATE GROUPS AND THEIR USE | BASF SE (DE) | 2020-03-04 | — | — | EP | claimed |
| EP-2760814-B1 | PROCESSES FOR SEPARATING COMPONENTS IN ALKYL PERFLUOROALKENE ETHER PRODUCTION | DU PONT (US) | 2015-10-28 | — | — | EP | claimed |
| EP-1319040-B1 | POLYMER-ORGANOCLAY COMPOSITE COMPOSITIONS, METHOD FOR MAKING AND ARTICLES THEREFROM | SABIC INNOVATIVE PLASTICS IP (NL) | 2014-08-20 | — | — | EP | claimed |
| EP-2072499-B1 | Method for manufacturing thiodiglycolic dialkyl esters | SALTIGO GMBH (DE) | 2012-02-22 | — | — | EP | claimed |
| JP-4750278-B2 | — | — | 2011-08-17 | — | — | JP | claimed |
| EP-1848702-A2 | PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS | Flexitral, Inc. (US) | 2007-10-31 | — | — | EP | claimed |
| WO-2006085048-A2 | PRO-FRAGRANCE AND PRO-FLAVORANT COMPOSITIONS | FLEXITRAL, INC. (US) | 2006-08-17 | — | — | WO | claimed |
| EP-1140054-B1 | BRETYLIUM COMPOSITIONS AND KITS, AND THEIR USE IN PREVENTING AND TREATING CARDIOVASCULAR CONDITIONS | BACANER MARVIN B (US) | 2005-03-16 | — | — | EP | claimed |
| EP-1390032-A4 | NOVEL QUATERNARY AMMONIUM COMPOSITIONS COUPLED WITH FACILITATING ANIONS AND THEIR USE IN KITS, AS WELL AS THEIR USE IN PREVENTING AND TREATING CERTAIN CONDITIONS | BACANER MARVIN B (US) | 2004-12-29 | — | — | EP | claimed |
| US-20030065015-A1 | Novel quarternary ammonium compositions coupled with facilitating anions and their use in kits, as well as their use in preventing and treating certain conditions | BACANER MARVIN B (US) | 2003-04-03 | — | — | US | claimed |
| WO-2002092003-A2 | NOVEL THERAPEUTICAL QUATERNARY AMMONIUM COMPOSITIONS | BACANER MARVIN B (US) | 2002-11-21 | — | — | WO | claimed |
| US-6482811-B1 | Bretylium compositions and kits, and their use in preventing and treating cardio-vascular conditions | BACANER MARVIN B (US) | 2002-11-19 | — | — | US | claimed |
| US-6423768-B1 | MIXTURES CONTAINING POLYAMIDES, POLYPHENYLENE ETHER AND IMPACT STRENGTH ADJUVANTS | GENERAL ELECTRIC COMPANY | 2002-07-23 | — | — | US | claimed |
| WO-2002022729-A1 | POLYMER-ORGANOCLAY COMPOSITE COMPOSITIONS, METHOD FOR MAKING AND ARTICLES THEREFROM | GENERAL ELECTRIC COMPANY (US) | 2002-03-21 | — | — | WO | claimed |
| EP-1140054-A2 | BRETYLIUM COMPOSITIONS AND KITS, AND THEIR USE IN PREVENTING AND TREATING CARDIOVASCULAR CONDITIONS | Bacaner, Marvin B. (US) | 2001-10-10 | — | — | EP | claimed |
| WO-2000040232-A2 | BRETYLIUM COMPOSITIONS AND KITS, AND THEIR USE IN PREVENTING AND TREATING CARDIOVASCULAR CONDITIONS | BACANER MARVIN B (US) | 2000-07-13 | — | — | WO | claimed |
| EP-0526401-B1 | Process for the preparation of glycidyl ethers of di-secondary alcohols with high monomer content | CIBA GEIGY AG (CH) | 1994-12-28 | — | — | EP | claimed |
| US-4430513-A | COBALT OR RHODIUM CARBONYL, CARBON-CARBON BOND FORMATION | UOP INC. (US) | 1984-02-07 | — | — | US | claimed |
| US-4196151-A | Process for producing β,γ-unsaturated aldehyde | NIPPON OIL AND FATS CO., LTD. (JP) | 1980-04-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065015-A1 | Novel quarternary ammonium compositions coupled with facilitating anions and their use in kits, as well as their use in preventing and treating certain conditions | SLC10A1, ATP6V1B1, SLC7A1 | OPRM1 3335/4885TP53 3326/4885SPHK1 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.