Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | BPTF | Q12830 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623456 | 0.88 | TSHR (0.52) | TUBB1TSHRMEN1KMT2AGAA | |
| SCHEMBL16654413 | 0.88 | POLB (0.47) | HTR2AHTR2CHTR2BBPTFCYP1A2 | |
| SCHEMBL6341314 | 0.85 | SMN1; SMN2 (0.47) | HTR2AHTR2CHTR2BTUBB1TUBB4A | |
| SCHEMBL6340052 | 0.81 | TNFRSF1A (0.47) | TSHRMAPTCYP3A4MAPK1 | |
| SCHEMBL24433 | 0.81 | CYP3A4 (0.56) | HTR2AHTR2CHTR2BTUBB1CYP1A1 | |
| SCHEMBL6339479 | 0.79 | MAPT (0.37) | HTR2AHTR2CHTR2BTUBB1CYP1A2 | |
| SCHEMBL5205549 | 0.78 | HTR2A (0.49) | HTR2AHTR2CHTR2BBPTFTUBB1 | |
| SCHEMBL16426991 | 0.78 | MAPT (0.54) | TSHRMAPTKDM4EGAAMAPK1 | |
| SCHEMBL1963060 | 0.78 | PDE4A (0.50) | TSHRMAPTKDM4EGAAMAPK1 | |
| SCHEMBL5623275 | 0.76 | LIPE (0.53) | MAPTMEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-6890940-B2 | Bis(2-aryl-5-pyridyl) derivatives | KOWA CO., LTD. (JP) | 2005-05-10 | — | — | US | disclosed |
| US-6787653-B2 | REACTING, IN THE PRESENCE OF A METAL CATALYST, A HALOGENOBENZOIC ACID DERIVATIVE WITH BENZENE DERIVATIVE TO PRODUCE BIPHENYLDICARBOXYLIC ACID AMIDE DERIVATIVE | KOWA CO., LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| WO-2003104213-A1 | PREPARATION PROCESS OF BIPHENYLCARBOXYLIC ACID AMIDE DERIVATIVES | KOWA CO., LTD. (JP) | 2003-12-18 | — | — | WO | disclosed |
| US-20030232992-A1 | Preparation process of biphenylcarboxylic acid amide derivatives | KOWA CO., LTD. (JP) | 2003-12-18 | — | — | US | disclosed |
| US-20030022886-A1 | Immoglobulin E (IgE) antibody production inhibitor; treating allergic immune diseases such as asthma, dermatitis, inflammatory bowel disease and allergic opthalmopathy | KOWA CO., LTD. (JP) | 2003-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022886-A1 | Immoglobulin E (IgE) antibody production inhibitor; treating allergic immune diseases such as asthma, dermatitis, inflammatory bowel disease and allergic opthalmopathy | IGLV6-57, IL5, IGSF11 | HTR2A 2586/4885HTR2C 2901/4885HTR2B 2979/4885 |
| US-20030232992-A1 | Preparation process of biphenylcarboxylic acid amide derivatives | CD22, C9, FCGR1A | HTR2A 3834/4885HTR2C 4029/4885HTR2B 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.