Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6337794 | 0.91 | MCHR1 (0.59) | MCHR1ACHEMAOBKCNH2MCHR2 | |
| SCHEMBL6338073 | 0.86 | MCHR1 (0.59) | MCHR1ACHEKCNH2NPC1RAB9A | |
| SCHEMBL6332263 | 0.86 | MCHR1 (0.57) | MCHR1ACHEMAOBKCNH2 | |
| SCHEMBL30578688 | 0.84 | RAB9A (0.57) | ALDH1A1KDM4ENPC1NR1I2HPGD | |
| SCHEMBL21062361 | 0.84 | RAB9A (0.57) | ALDH1A1KDM4ENPC1NR1I2HPGD | |
| Hydrochloric Acid SCHEMBL21050122 | 0.83 | RAB9A (0.56) | ALDH1A1KDM4ENPC1NR1I2HPGD | |
| SCHEMBL6329928 | 0.82 | MCHR1 (0.55) | MCHR1ACHEMAOBKCNH2MCHR2 | |
| SCHEMBL6333533 | 0.82 | MCHR1 (0.60) | MCHR1ACHEMAOBKCNH2MCHR2 | |
| SCHEMBL6331471 | 0.81 | MCHR1 (0.56) | MCHR1ACHEMAOBKCNH2MCHR2 | |
| SCHEMBL6329320 | 0.79 | MCHR1 (0.67) | MCHR1KCNH2MCHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABOTT LABORATORIES | 2005-09-22 | — | — | US | disclosed |
| US-20050187387-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | ABBOTT LABORATORIES | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209274-A1 | Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor | MCHR1, MCHR2, MC1R | MCHR1 1/4885ALDH1A1 1308/4885ACHE 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.