SCHEMBL6338048

SCHEMBL6338048

O=C(O)c1ccc(S(=O)(=O)O)c(-c2ccccc2S(=O)(=O)O)c1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
HSD17B10 Q99714 2/20 0.45
CYP2C9 P11712 1/20 0.45
HIF1A Q16665 1/20 0.45
MAPT P10636 7/20 0.42
ALDH1A1 P00352 6/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
LMNA P02545 2/20 0.42
KMT2A Q03164 5/20 0.42
MEN1 O00255 4/20 0.42
MAPK1 P28482 3/20 0.42
THRB P10828 2/20 0.42
PGAM1 P18669 1/20 0.42
POLB P06746 1/20 0.42
RECQL P46063 1/20 0.42
KDM4E B2RXH2 2/20 0.41
USP2 O75604 2/20 0.41
PKM P14618 1/20 0.41
MCL1 Q07820 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2548805 0.84 CYP2D6 (0.48) TSHRHSD17B10CYP2C9HIF1AALDH1A1
SCHEMBL751336 0.84 CA1 (0.41) TSHRHSD17B10CYP2C9HIF1AMAPT
SCHEMBL6249607 0.82 ALDH1A1 (0.46) TSHRHSD17B10CYP2C9HIF1AMAPT
SCHEMBL6296808 0.76 ALDH1A1 (0.47) TSHRHSD17B10CYP2C9HIF1AALDH1A1
SCHEMBL8606449 0.76 HSD17B10 (0.42) TSHRHSD17B10CYP2C9HIF1AALDH1A1
SCHEMBL30705724 0.76 HSD17B10 (0.42) TSHRHSD17B10CYP2C9HIF1AALDH1A1
SCHEMBL751983 0.76 CYP2D6 (0.52) TSHRHSD17B10CYP2C9HIF1AALDH1A1
SCHEMBL8664882 0.76 FOLH1 (0.50) TSHRHSD17B10CYP2C9HIF1AMAPT
SCHEMBL3268626 0.76 ALDH1A1 (0.54) TSHRHSD17B10CYP2C9HIF1AMAPT
Phthalic Acid SCHEMBL4279595 0.75 ALOX15 (0.52) TSHRHSD17B10CYP2C9ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916481-B1 Active-substance vector multiparticulate system, production and use thereof Chimie, Rhodia (FR) 2005-07-12 US disclosed
EP-1169425-B1 ACTIVE-SUBSTANCE VECTOR MULTIPARTICULATE SYSTEM, PRODUCTION AND USE THEREOF RHODIA CHIMIE SA (FR) 2004-12-22 EP disclosed