Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | FABP1 | P07148 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28423664 | 0.81 | HTT (0.54) | AKR1C3TTRMEN1KMT2ATSHR | |
| SCHEMBL6340212 | 0.81 | TTR (0.60) | AKR1C3TTRMEN1KMT2AMRGPRX4 | |
| SCHEMBL6343006 | 0.79 | AKR1C3 (0.47) | AKR1C3TTRMEN1KMT2AMRGPRX4 | |
| SCHEMBL6341056 | 0.79 | MRGPRX4 (0.55) | AKR1C3TTRMEN1KMT2AMRGPRX4 | |
| SCHEMBL6341195 | 0.79 | GAA (0.50) | AKR1C3TTRMEN1KMT2ADHODH | |
| SCHEMBL1768785 | 0.77 | AKR1C3 (0.74) | AKR1C3TTRMEN1KMT2ASRD5A2 | |
| SCHEMBL28080606 | 0.77 | HTT (0.54) | AKR1C3TTRMEN1KMT2ATSHR | |
| SCHEMBL28264709 | 0.76 | HTT (0.53) | AKR1C3TTRMEN1KMT2ATSHR | |
| SCHEMBL28032723 | 0.76 | SRD5A2 (0.56) | SRD5A2 | |
| SCHEMBL1195534 | 0.76 | LCK (0.44) | AKR1C3TTRMEN1KMT2AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949674-B2 | Aromatic carboxylic acids, acid halides thereof and processes for preparing both | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20040068139-A1 | Aromatic carboxylic acids, acid halides thereof and processes for preparing both | SUMITOMO BAKELITE COMPANY, LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| EP-1346975-A1 | AROMATIC CARBOXYLIC ACIDS, ACID HALIDES THEREOF AND PROCESSES FOR PREPARING BOTH | SUMITOMO BAKELITE CO., LTD. (JP) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040068139-A1 | Aromatic carboxylic acids, acid halides thereof and processes for preparing both | CCR1, CCRL2, CCR6 | AKR1C3 137/4885TTR 1607/4885MEN1 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.