Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6338024 | 0.92 | PDE1C (0.50) | ALDH1A1NPSR1HSD17B10LMNAPOLB | |
| SCHEMBL6340731 | 0.88 | CACNA1F (0.43) | NPSR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6338173 | 0.86 | PDE1C (0.53) | NPSR1PDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL6336408 | 0.83 | PDE1C (0.57) | NPSR1HSD17B10PDE1CCACNA1FCACNA1D | |
| SCHEMBL6339672 | 0.81 | PDE1C (0.52) | NPSR1PDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL6347405 | 0.81 | CACNA1F (0.67) | ALDH1A1NPSR1PDE1CCACNA1FCACNA1D | |
| SCHEMBL6340251 | 0.81 | ADRA1D (0.54) | ALDH1A1NPSR1HSD17B10LMNAPOLB | |
| SCHEMBL6346164 | 0.79 | PDE1C (0.62) | NPSR1PDE1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL6340739 | 0.79 | CACNA1F (0.45) | NPSR1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL6338019 | 0.76 | ADRA1D (0.55) | ALDH1A1NPSR1HSD17B10PDE1CCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855716-B2 | Dihydropyrimidine compounds and compositions containing the same | AJINOMOTO CO., INC. (JP) | 2005-02-15 | — | — | US | disclosed |
| US-20020143023-A1 | Dihydropyrimidine compounds and compositions containing the same | AJINOMOTO CO. INC (JP) | 2002-10-03 | — | — | US | disclosed |
| EP-1193259-A1 | DIHYDROPYRIMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2002-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143023-A1 | Dihydropyrimidine compounds and compositions containing the same | CACNA1B, CACNA1D, CACNA1G | ALDH1A1 2543/4885NPSR1 1955/4885HSD17B10 3690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.