SCHEMBL634032

SCHEMBL634032

COC(=O)[C@H](CCCCN)NC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.46
ANPEP P15144 1/20 0.45
ERAP2 Q6P179 6/20 0.43
LNPEP Q9UIQ6 6/20 0.43
CPB2 Q96IY4 1/20 0.42
ERAP1 Q9NZ08 2/20 0.42
CNR2 P34972 1/20 0.42
GSR P00390 1/20 0.41
RNPEP Q9H4A4 1/20 0.40
SIRT6 Q8N6T7 1/20 0.40
SIRT1 Q96EB6 1/20 0.40
SLC6A5 Q9Y345 1/20 0.40
GHSR Q92847 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21879807 0.88 CPB2 (0.53) FOLH1CPB2GSRRNPEPSIRT6
SCHEMBL28085656 0.87 FOLH1 (0.47) FOLH1ANPEPCPB2GSRRNPEP
SCHEMBL15148580 0.86 ERAP2 (0.43) FOLH1ANPEPERAP2LNPEPCPB2
SCHEMBL5494276 0.86 SIRT6 (0.54) FOLH1ANPEPERAP2LNPEPERAP1
SCHEMBL27507131 0.86 FOLH1 (0.46) FOLH1ANPEPCPB2GSRRNPEP
SCHEMBL2387748 0.86 SIRT6 (0.54) FOLH1ANPEPERAP2LNPEPERAP1
Hydrochloric Acid SCHEMBL2122177 0.84 SIRT6 (0.52) FOLH1ANPEPERAP2LNPEPERAP1
Hydrochloric Acid SCHEMBL2122175 0.84 SIRT6 (0.52) FOLH1ANPEPERAP2LNPEPERAP1
SCHEMBL5333662 0.84 ERAP2 (0.45) FOLH1ANPEPERAP2LNPEPERAP1
SCHEMBL5333660 0.84 ERAP2 (0.45) FOLH1ANPEPERAP2LNPEPERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103293243-B Detection method and application of carboxy methyl lysine ingredient in food FUJIAN INSPECTION AND RES INST FOR PRODUCT QUALITY 2015-05-13 CN claimed
US-20240218373-A1 METHODS AND COMPOSITIONS FOR TREATING NEUROINFLAMMATION AIM IMMUNOTECH INC. (US) 2024-07-04 US disclosed
EP-4388101-A1 COMPOSITIONS AND METHODS FOR TREATING POST-COVID CONDITIONS OF FATIGUE AIM ImmunoTech Inc. (US) 2024-06-26 EP disclosed
EP-4334451-A1 METHODS AND COMPOSITIONS FOR TREATING NEUROINFLAMMATION AIM ImmunoTech Inc. (US) 2024-03-13 EP disclosed
US-11813281-B2 Methods for improving exercise tolerance in myalgic encephalomyelitis patients AIM IMMUNOTECH INC. (US) 2023-11-14 US disclosed
WO-2023049904-A1 COMPOSITIONS AND METHODS FOR ENHANCING AND EXPANDING INFECTION INDUCED IMMUNITY AIM IMMUNOTECH INC. (US) 2023-03-30 WO disclosed
WO-2023023676-A1 COMPOSITIONS AND METHODS FOR TREATING POST-COVID CONDITIONS OF FATIGUE AIM IMMUNOTECH INC. (US) 2023-02-23 WO disclosed
US-20220387475-A1 METHODS AND COMPOSITIONS FOR TREATING ENDOMETRIOSIS AIM IMMUNOTECH INC. (US) 2022-12-08 US disclosed
US-20220387472-A1 COMPOSITIONS AND METHODS FOR TREATING CANCER AIM IMMUNOTECH INC. (US) 2022-12-08 US disclosed
US-20220389058-A1 PEPTIDES AND COMPOSITIONS FOR USE IN COSMETICS AND MEDICINE LIPOTRUE, S.L. (ES) 2022-12-08 US disclosed
WO-2007121922-A2 BIOMARKERS FOR CHRONIC TRANSPLANT DYSFUNCTION NOVARTIS AG (CH) 2007-11-01 WO disclosed
US-7258857-B2 Rage-related methods for treating inflammation THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2007-08-21 US disclosed
US-20060111292-A1 Compositions for mucosal and oral administration comprising HCG fragments BIOTEMPT, B.V. (NL) 2006-05-25 US disclosed
EP-1615655-A1 COMPOSITIONS FOR MUCOSAL AND ORAL ADMINISTRATION COMPRISING HCG FRAGMENTS Biotempt B.V. (NL) 2006-01-18 EP disclosed
WO-2004093897-A1 COMPOSITIONS FOR MUCOSAL AND ORAL ADMINISTRATION COMPRISING HCG FRAGMENTS BIOTEMPT, B.V. (NL) 2004-11-04 WO disclosed
US-20040210042-A1 Polypeptides relating to signal transfer of advanced glycation end product receptor MITSUBISHI PHARMA CORPORATION (JP) 2004-10-21 US disclosed
US-20040202645-A1 Administration of gene-regulatory peptides BIOTEMPT B.V. (NL) 2004-10-14 US disclosed
EP-1466613-A1 Compositions for mucosal and oral administration comprising hCG fragments Biotempt B.V. (NL) 2004-10-13 EP disclosed
EP-1415997-A1 POLYPEPTIDES RELATING TO SIGNAL TRANSFER OF ADVANCED GLYCATION END PRODUCT RECEPTOR Mitsubishi Pharma Corporation (JP) 2004-05-06 EP disclosed
US-20020122799-A1 Methods for treating inflammation TRANSTECH PHARMA, INC. 2002-09-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218373-A1 METHODS AND COMPOSITIONS FOR TREATING NEUROINFLAMMATION ELAVL1, ELAVL3, SYNCRIP FOLH1 2235/4885ANPEP 3070/4885ERAP2 1658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.