SCHEMBL634033

SCHEMBL634033

CN(C(=O)O)[C@@H](CCCCN)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.48
RNPEP Q9H4A4 1/20 0.47
CPB2 Q96IY4 6/20 0.45
GABRR1 P24046 2/20 0.38
FOLH1 Q04609 1/20 0.38
EPOR P19235 1/20 0.36
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
F2 P00734 1/20 0.35
BLM P54132 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PLG P00747 1/20 0.34
LMNA P02545 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
SLC6A2 P23975 1/20 0.34
RECQL P46063 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2725758 1.00 GSR (0.48) GSRRNPEPCPB2GABRR1FOLH1
SCHEMBL15641942 0.87 RNPEP (0.50) GSRRNPEPCPB2GABRR1FOLH1
SCHEMBL19385944 0.87 RNPEP (0.50) GSRRNPEPCPB2GABRR1FOLH1
SCHEMBL15641943 0.87 RNPEP (0.50) GSRRNPEPCPB2GABRR1FOLH1
SCHEMBL181034 0.84 GSR (0.52) GSRRNPEPCPB2GABRR1FOLH1
SCHEMBL4735950 0.84 GSR (0.52) GSRRNPEPCPB2GABRR1FOLH1
SCHEMBL181035 0.84 GSR (0.52) GSRRNPEPCPB2GABRR1FOLH1
Lysine SCHEMBL9746892 0.83 GSR (0.57) GSRRNPEPCPB2BLM
SCHEMBL18531957 0.82 GSR (0.50) GSRRNPEPCPB2GABRR1FOLH1
SCHEMBL2821712 0.82 GSR (0.50) GSRRNPEPCPB2GABRR1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025560-A1 METHOD FOR THE REVIVAL OF MICROGLIA AND ASTROCYTES AND APPLICATIONS THEREOF UNIVERSITY OF SOUTH CAROLINA 2025-01-23 US claimed
CN-103293243-B Detection method and application of carboxy methyl lysine ingredient in food FUJIAN INSPECTION AND RES INST FOR PRODUCT QUALITY 2015-05-13 CN claimed
EP-4577218-A1 NUTRACEUTICAL COMPOSITIONS AND METHODS FOR USING SAME Mary Kay Inc. (US) 2025-07-02 EP disclosed
US-20250025560-A1 METHOD FOR THE REVIVAL OF MICROGLIA AND ASTROCYTES AND APPLICATIONS THEREOF UNIVERSITY OF SOUTH CAROLINA 2025-01-23 US disclosed
US-20240360171-A1 ADVANCED GLYCATION END PRODUCT ANALOGUES PHYTOQUEST LIMITED (GB) 2024-10-31 US disclosed
US-11970513-B2 Advanced glycation end product analogues PHYTOQUEST LIMITED (GB) 2024-04-30 US disclosed
WO-2024044773-A1 NUTRACEUTICAL COMPOSITIONS AND METHODS FOR USING SAME MARY KAY INC. (US) 2024-02-29 WO disclosed
US-11903392-B2 Hypoallergenic infant formula and methods for preparing the same FRIESLANDCAMPINA NEDERLAND B.V. (NL) 2024-02-20 US disclosed
US-20230048369-A1 POLYOXAZOLINE MODIFICATIONS MITIGATE STRUCTURAL DEGENERATION OF BIOPROSTHETIC HEART VALVES THE CHILDREN'S HOSPITAL OF PHILADELPHIA 2023-02-16 US disclosed
EP-4090323-A1 POLYOXAZOLINE MODIFICATIONS MITIGATE STRUCTURAL DEGENERATION OF BIOPROSTHETIC HEART VALVES The Trustees of Columbia University in the City of New York (US) 2022-11-23 EP disclosed
EP-4091622-A1 COMPOSITIONS FOR THE TREATMENT OF CHEMOTHERAPY-INDUCED NEUROPATHIC PAIN Henry Ford Health System (US) 2022-11-23 EP disclosed
US-20020122799-A1 Methods for treating inflammation TRANSTECH PHARMA, INC. 2002-09-05 US disclosed
WO-2002050548-A1 DETECTION OF ADVANCED GLYCATION ENDPRODUCTS IN A CEREBROSPINAL FLUID SAMPLE ROCHE DIAGNOSTICS GMBH (DE) 2002-06-27 WO disclosed
EP-1217378-A1 Detection of advanced glycation endproducts in a cerebrospinal fluid sample Roche Diagnostics GmbH (DE) 2002-06-26 EP disclosed
US-6380165-B1 THAT IS ANTIGENIC AND USEFUL FOR FORMING ANTIBODIES HAVING UTILITY IN STANDARDIZING DIAGNOSTIC ASSAYS, COMPRISING A LYSINE COMPONENT, AN ARGININE COMPONENT AND A REDUCING SUGAR COMPONENT THE PICOWER INSTITUTE FOR MEDICAL RESEARCH 2002-04-30 US disclosed
US-6369106-B1 SULFHYDRYL CONTAINING COMPOUND AS ANTIOXIDANT YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2002-04-09 US disclosed
US-20020022234-A1 IMMUNOLOGICAL ADVANCED GLYCATION ENDPRODUCT CROSSLINK PICOWER INSTITUTE FOR MEDICAL RESEARCH 2002-02-21 US disclosed
WO-2001047469-A2 TREATMENT OF ISCHEMIC BRAIN INJURIES WITH BRAIN TARGETTED ANTIOXIDANT COMPOUNDS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2001-07-05 WO disclosed
EP-1018005-A1 METHODS FOR MEASURING AND ELIMINATING ADVANCED GLYCATION ENDPRODUCTS THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 2000-07-12 EP disclosed
WO-1999014587-A1 METHODS FOR MEASURING AND ELIMINATING ADVANCED GLYCATION ENDPRODUCTS THE PICOWER INSTITUTE FOR MEDICAL RESEARCH (US) 1999-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970513-B2 Advanced glycation end product analogues AGER, SI, GALE GSR 774/4885RNPEP 170/4885CPB2 2414/4885
US-20240360171-A1 ADVANCED GLYCATION END PRODUCT ANALOGUES AGER, GALE, SI GSR 727/4885RNPEP 175/4885CPB2 2613/4885
US-20250025560-A1 METHOD FOR THE REVIVAL OF MICROGLIA AND ASTROCYTES AND APPLICATIONS THEREOF L1CAM, CD274, PDCD1LG2 GSR 592/4885RNPEP 1788/4885CPB2 4722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.