SCHEMBL634041

SCHEMBL634041

CCS(=O)(=O)c1ccc(O)c(N)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.66
MAPT P10636 3/20 0.66
CA2 P00918 2/20 0.66
CA12 O43570 1/20 0.66
CA1 P00915 1/20 0.66
CA9 Q16790 1/20 0.66
ALDH1A1 P00352 6/20 0.63
HSD17B10 Q99714 4/20 0.63
ALOX15 P16050 2/20 0.49
PKM P14618 2/20 0.49
HPGD P15428 2/20 0.49
USP2 O75604 1/20 0.49
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
CYP2D6 P10635 1/20 0.47
PSIP1 O75475 2/20 0.46
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9497123 0.98 GAA (0.63) GAAMAPTCA2CA12CA1
SCHEMBL10348670 0.87 CA2 (0.59) GAAMAPTCA2CA12CA1
SCHEMBL11222680 0.85 GAA (0.52) GAAMAPTCA2CA12CA1
SCHEMBL28100405 0.85 GAA (0.66) GAAMAPTCA2CA12CA1
SCHEMBL7070254 0.84 CA2 (0.56) GAAMAPTCA2CA12CA1
Betanaphthol SCHEMBL11875994 0.84 GAA (0.47) GAAMAPTCA2CA12CA1
SCHEMBL11789980 0.83 GAA (0.63) GAAMAPTCA2CA12CA1
SCHEMBL10910948 0.83 CA2 (0.63) GAAMAPTCA2CA12CA1
SCHEMBL11561407 0.82 GAA (0.57) GAAMAPTCA2CA12CA1
SCHEMBL5677264 0.81 CA2 (0.61) GAAMAPTCA2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105566182-B A kind of 2 amino 4(Ethylsulfonyl)The synthetic method of phenol 苏州天马精细化学品股份有限公司 2018-02-13 CN claimed
CN-105566182-A Synthetic method of 2-amino-4-(ethylsulfonyl) phenol SUZHOU TIANMA SPECIALTY CHEMICALS CO LTD 2016-05-11 CN claimed
US-20100166765-A1 BENZOQUINAZOLINE DERIVATIVES NOVARTIS AG (CH) 2010-07-01 US claimed
EP-1917246-B1 BENZOQUINAZOLINE DERIVATIVES AND THEIR USE IN TREATING BONE DISORDERS NOVARTIS AG (CH) 2009-11-11 EP claimed
EP-1917246-A1 BENZOQUINAZOLINE DERIVATIVES AND THEIR USE IN TREATING BONE DISORDERS Novartis AG (CH) 2008-05-07 EP claimed
WO-2007020046-A1 BENZOQUINAZOLINE DERIVATIVES AND THEIR USE IN TREATING BONE DISORDERS NOVARTIS AG (CH) 2007-02-22 WO claimed
US-6461417-B1 Ink compositions XEROX CORPORATION 2002-10-08 US claimed
US-5264139-A Antioxidant dispersant antiwear VI improver additive and lubricating oil composition containing same TEXACO INC. (US) 1993-11-23 US claimed
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME CHECKMATE THERAPEUTICS INC. (KR) 2026-01-22 US disclosed
WO-2023229346-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME 주식회사 체크메이트테라퓨틱스 2023-11-30 WO disclosed
EP-3369726-B1 METHOD FOR PRODUCING 2-AMINO-4-SUBSTITUTED PHENOL SUMITOMO CHEMICAL CO (JP) 2020-08-26 EP disclosed
CN-108349884-B Process for producing 2-amino-4-substituted phenol 住友化学株式会社 2020-04-21 CN disclosed
CN-110437170-A A kind of synthesis technology according to pearl song rice UNIV EAST CHINA NORMAL 2019-11-12 CN disclosed
EP-3500245-A1 COMPOSITION FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Summit (Oxford) Limited (GB) 2019-06-26 EP disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4005065-A GOOD FASTNESS TO LIGHT, PERSPIRATION, FULLING, DECATIZING AND CARBONIZING CIBA-GEIGY CORPORATION (US) 1977-01-25 US disclosed
US-3993659-A Bis-benzoxazolyl-naphthalenes as optical brighteners CIBA-GEIGY CORPORATION (US) 1976-11-23 US disclosed
US-3985763-A DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100166765-A1 BENZOQUINAZOLINE DERIVATIVES CACNA1A, BMP4, TPX2 GAA 1216/4885MAPT 4506/4885CA2 22/4885
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME NAMPT, NAPRT, NNT GAA 2409/4885MAPT 1402/4885CA2 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.