Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.59 |
| ▸ | CCR5 | P51681 | 14/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.42 |
| ▸ | CCR7 | P32248 | 2/20 | 0.42 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6340391 | 0.93 | CCR2 (0.61) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL6349338 | 0.88 | CCR2 (0.60) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL6353376 | 0.88 | CCR2 (0.60) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL6351839 | 0.87 | CCR2 (0.59) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL5205469 | 0.85 | CCR2 (0.63) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL3026568 | 0.84 | CCR2 (0.63) | CCR2CCR5 | |
| SCHEMBL5206259 | 0.84 | CCR2 (0.62) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL6343365 | 0.83 | CCR2 (0.63) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL7866956 | 0.82 | CCR2 (0.61) | CCR2CCR5MCHR1CXCR3CCR7 | |
| SCHEMBL5209291 | 0.82 | CCR2 (0.64) | CCR2CCR5CXCR3CCR7CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936602-B1 | Benzazepine derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-30 | — | — | US | disclosed |
| EP-1186604-A1 | BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-13 | — | — | EP | disclosed |