Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266814 | 0.87 | CA12 (0.51) | CA12CA2CA9MAPTKDM4E | |
| SCHEMBL7157513 | 0.85 | CA12 (0.58) | CA12CA2CA9MAPTKDM4E | |
| SCHEMBL6346080 | 0.85 | MAPT (0.43) | CA12CA2CA9MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL28825273 | 0.84 | CA12 (0.56) | CA12CA2CA9MAPTKDM4E | |
| SCHEMBL5159609 | 0.79 | MAPT (0.53) | CA12CA2CA9MAPTKMT2A | |
| SCHEMBL27575529 | 0.77 | CA12 (0.51) | CA12CA2CA9MAPTKDM4E | |
| SCHEMBL6738506 | 0.77 | PRKCI (0.42) | CA12CA2CA9MAPTKDM4E | |
| SCHEMBL10955924 | 0.76 | PRKCI (0.49) | CA12CA2CA9MAPTKDM4E | |
| SCHEMBL6739748 | 0.75 | CA12 (0.45) | CA12CA2CA9MAPTKDM4E | |
| SCHEMBL10782516 | 0.75 | CA12 (0.88) | CA12CA2CA9MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936077-B2 | 1,3-diamino-4-(aminomethyl)—benzene derivatives and colorants containing the said compounds | WELLA AG (DE) | 2005-08-30 | — | — | US | disclosed |
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030172471-A1 | 1,3-diamino-4-(aminomethyl) - benzene derivatives and colorants containing the said compounds | AOC1, DPYD, NDUFB4 | CA12 3504/4885CA2 2409/4885CA9 2974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.