Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28439458 | 0.79 | TDP1 (0.49) | POLBARAPPFBP1RAB9A | |
| SCHEMBL6624649 | 0.75 | CA12 (0.53) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL27826601 | 0.75 | HTT (0.45) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL16862940 | 0.74 | TDP1 (0.47) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL9488402 | 0.74 | SLC6A3 (0.63) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL3021443 | 0.73 | POLB (0.73) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL11398188 | 0.73 | TDP1 (0.56) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL13712890 | 0.72 | SLC6A3 (0.53) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL29242434 | 0.72 | MEN1 (0.62) | MEN1KMT2AMAPTGAAHTT | |
| SCHEMBL773633 | 0.72 | TDP1 (0.59) | MEN1KMT2AMAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894174-B1 | Water-soluble polyimides and methods of making and using same | SHAYDA TECHNOLOGIES, INC. (US) | 2005-05-17 | — | — | US | disclosed |