Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | DRD3 | P35462 | 5/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6337152 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CYP2D6CYP2C9ALOX15MAPK1 | |
| SCHEMBL6334373 | 0.92 | ALDH1A1 (0.49) | ALDH1A1CYP2D6CYP2C9ALOX15MAPK1 | |
| SCHEMBL6337111 | 0.88 | DRD2 (0.60) | CYP2D6DRD2DRD3DRD4 | |
| SCHEMBL6346693 | 0.88 | DRD3 (0.60) | DRD2DRD3DRD4 | |
| SCHEMBL6336517 | 0.88 | DRD2 (0.60) | CYP2D6DRD2DRD3DRD4 | |
| SCHEMBL6343814 | 0.88 | ALDH1A1 (0.51) | ALDH1A1CYP2D6CYP2C9ALOX15MAPK1 | |
| SCHEMBL3388549 | 0.86 | ALDH1A1 (0.49) | ALDH1A1CYP2D6CYP2C9ALOX15MAPK1 | |
| SCHEMBL6336486 | 0.86 | ALDH1A1 (0.49) | ALDH1A1CYP2D6CYP2C9ALOX15MAPK1 | |
| SCHEMBL5216026 | 0.86 | ALDH1A1 (0.44) | ALDH1A1CYP2D6CYP2C9ALOX15MAPK1 | |
| SCHEMBL6344274 | 0.85 | ALDH1A1 (0.48) | ALDH1A1CYP2D6CYP2C9ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864266-B2 | 4-piperidinyl alkyl amine derivatives as muscarinic receptor antagonists | SYNTEX (U.S.A.) LLC (US) | 2005-03-08 | — | — | US | claimed |