Uric Acid

Uric Acid

SCHEMBL6341111

CC(O)C(O)(O)C(=O)c1ccccc1.O=c1[nH]c(=O)c2[nH]c(=O)[nH]c2[nH]1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.43
CES1 P23141 2/20 0.35
SRC P12931 1/20 0.35
MLYCD O95822 1/20 0.35
LMNA P02545 2/20 0.33
ALDH1A1 P00352 5/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
GAA P10253 2/20 0.33
HPGD P15428 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
BLM P54132 1/20 0.33
MAPK10 P53779 1/20 0.32
ADORA2B P29275 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TK1 P04183 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43695 0.81 CES1 (0.48) CES1SRCMLYCDLMNAALDH1A1
Benzophenone SCHEMBL28091624 0.78 GDA (0.57) GDALMNAALDH1A1MEN1KMT2A
Urea SCHEMBL28087882 0.76 CES1 (0.44) CES1SRCMLYCDLMNAALDH1A1
Uric Acid SCHEMBL27584014 0.74 GDA (0.48) GDACES1LMNAALDH1A1MEN1
Uric Acid SCHEMBL28187122 0.74 GDA (0.61) GDAALDH1A1GAAHPGDMAPT
Uric Acid SCHEMBL28282520 0.70 GDA (0.67) GDAALDH1A1GAAHPGDADORA2B
Uric Acid SCHEMBL28093010 0.70 GDA (0.73) GDAALDH1A1GAAHPGDMAPT
Uric Acid SCHEMBL27816624 0.70 GDA (0.89) GDAALDH1A1GAAHPGDMAPT
Uric Acid SCHEMBL1893296 0.68 GDA (0.76) GDALMNAALDH1A1GAAHPGD
Uric Acid SCHEMBL27945078 0.68 GDA (0.61) GDAALDH1A1GAAHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103717074-B Composition comprising isosorbide monoester and alcohol comprising at least one aromatic group 克拉里安特国际有限公司 2016-07-13 CN disclosed
US-6911210-B1 Stable active ingredient combinations which are effective against blemished skin and against acne and contain interface-active glucose derivatives and hydroxycarbolic acids BEIERSDORF AG (DE) 2005-06-28 US disclosed