SCHEMBL634142

SCHEMBL634142

C=Cc1cc2ccc3cccc4ccc(c1S(=O)(=O)O)c2c34

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.40
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40
AHR P35869 1/20 0.40
ALDH1A1 P00352 6/20 0.38
HPGD P15428 5/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
CYP2D6 P10635 2/20 0.35
SLC9A1 P19634 2/20 0.35
HSD17B10 Q99714 5/20 0.35
TSHR P16473 3/20 0.35
CYP3A4 P08684 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GUSB P08236 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3712353 0.89 CYP1A2 (0.35) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL3723434 0.79 ALDH1A1 (0.36) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL222715 0.78 CYP1A2 (0.44) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL1132745 0.78 CYP1A2 (0.49) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL18171072 0.78 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL28398046 0.77 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL3697272 0.77 CYP1A2 (0.43) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL28935980 0.77 CYP1A2 (0.43) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL636044 0.77 CYP2D6 (0.37) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL27278262 0.76 CYP1A2 (0.46) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1825057-B1 RETENTION AND DRAINAGE AIDS SOLENIS TECHNOLOGIES CAYMAN LP (CH) 2015-04-22 EP claimed
CN-101080533-B Retention and drainage aids HERCULES INC 2012-05-30 CN claimed
US-7615135-B2 Retention and drainage aids HERCULES INCORPORATED (US) 2009-11-10 US claimed
JP-2008523235-A 2008-07-03 JP claimed
CN-101155835-A Process for preparing high molar mass polymers HERCULES INC (US) 2008-04-02 CN claimed
CN-101080533-A Retention and drainage aids HERCULES INC (US) 2007-11-28 CN claimed
EP-1844079-A1 PROCESS FOR PREPARING HIGH MOLAR MASS POLYMERS Hercules Incorporated (US) 2007-10-17 EP claimed
EP-1825057-A2 RETENTION AND DRAINAGE AIDS HERCULES INCORPORATED (US) 2007-08-29 EP claimed
US-20060185806-A1 Retention and drainage aids THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2006-08-24 US claimed
WO-2006065927-A1 PROCESS FOR PREPARING HIGH MOLAR MASS POLYMERS HERCULES INCORPORATED (US) 2006-06-22 WO claimed
WO-2006065928-A2 RETENTION AND DRAINAGE AIDS HERCULES INCORPORATED (US) 2006-06-22 WO claimed
US-20060127351-A1 Process for preparing high molar mass polymers HERCULES INCORPORATED (US) 2006-06-15 US claimed
EP-1825057-B1 RETENTION AND DRAINAGE AIDS SOLENIS TECHNOLOGIES CAYMAN LP (CH) 2015-04-22 EP disclosed
CN-101080533-B Retention and drainage aids HERCULES INC 2012-05-30 CN disclosed
US-8137860-B2 Polymer electrolyte membrane for solid polymer fuel cell, membrane-electrode assembly and fuel cell KURARAY CO., LTD. (JP) 2012-03-20 US disclosed
EP-1840993-B1 POLYMER ELECTROLYTE MEMBRANE FOR SOLID POLYMER FUEL CELL, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL KURARAY CO (JP) 2012-02-22 EP disclosed
US-20060185806-A1 Retention and drainage aids THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2006-08-24 US disclosed
WO-2006065927-A1 PROCESS FOR PREPARING HIGH MOLAR MASS POLYMERS HERCULES INCORPORATED (US) 2006-06-22 WO disclosed
WO-2006065928-A2 RETENTION AND DRAINAGE AIDS HERCULES INCORPORATED (US) 2006-06-22 WO disclosed
US-20060127351-A1 Process for preparing high molar mass polymers HERCULES INCORPORATED (US) 2006-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060127351-A1 Process for preparing high molar mass polymers POLM, PHOSPHO1, AGPS CYP1A2 2246/4885ERBB2 3417/4885FYN 2777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.