SCHEMBL634152

SCHEMBL634152

Cc1cc(Cl)cc2c(=O)oc(=O)[nH]c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.38
F2 P00734 1/20 0.37
CFD P00746 1/20 0.37
PDGFRA P16234 1/20 0.37
MAPK8 P45983 1/20 0.37
CDK5 Q00535 1/20 0.37
CLK4 Q9HAZ1 1/20 0.37
AHR P35869 1/20 0.36
NOTUM Q6P988 1/20 0.36
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP1A2 P05177 3/20 0.35
NOS1 P29475 2/20 0.35
ADRA2A P08913 1/20 0.35
TSHR P16473 1/20 0.35
NOS3 P29474 1/20 0.35
NOS2 P35228 1/20 0.35
THPO P40225 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30087001 1.00 LMNA (0.38) LMNAF2CFDPDGFRAMAPK8
SCHEMBL30804569 0.82 HSD17B10 (0.43) LMNAF2CFDAHRCYP1A2
SCHEMBL2061473 0.82 HSD17B10 (0.43) LMNAF2CFDAHRCYP1A2
SCHEMBL5280067 0.82 ABCB1 (0.46) F2CFDPDGFRAMAPK8CDK5
SCHEMBL14698539 0.81 F2 (0.36) LMNAF2CFDPDGFRAMAPK8
SCHEMBL13208799 0.79 F2 (0.37) F2CFDPDGFRAMAPK8CDK5
SCHEMBL14698281 0.79 F2 (0.37) LMNAF2CFDPDGFRAMAPK8
SCHEMBL2906293 0.79 F2 (0.37) F2CFDPDGFRAMAPK8CDK5
SCHEMBL3208633 0.79 GSK3B (0.38) LMNAF2CFDPDGFRAMAPK8
SCHEMBL14698434 0.79 F2 (0.37) F2CFDPDGFRAMAPK8CDK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115594608-A Preparation method of chlorantraniliprole intermediate 九江善水科技股份有限公司(CN) 2023-01-13 CN claimed
EP-4605373-A1 METHOD FOR PREPARING CHLORINE-CONTAINING BENZAMIDE DERIVATIVES FMC Corporation (US) 2025-08-27 EP disclosed
CN-115536540-B Efficient novel method for synthesizing 2-amino-5-chloro-N, 3-dimethylbenzamide FMC公司 2025-03-25 CN disclosed
CN-114621130-B Efficient novel method for synthesizing 2-amino-5-chloro-N, 3-dimethylbenzamide FMC公司 2025-02-25 CN disclosed
CN-119462601-A Anthranilamide compound, preparation method thereof and application of anthranilamide compound as pesticide 扬州工业职业技术学院 2025-02-18 CN disclosed
EP-3927701-B1 A PROCESS FOR PREPARING ANTHRANILIC DIAMIDES AND INTERMEDIATES THEREOF PI INDUSTRIES LTD (IN) 2024-11-06 EP disclosed
CN-113692406-B Process for preparing anthranilamide compounds and intermediates thereof PI工业有限公司 2024-07-23 CN disclosed
WO-2024105700-A1 A METHOD FOR THE SYNTHESIS OF ANTHRANILIC AMIDE COMPOUNDS AND INTERMEDIATES THEREOF PI INDUSTRIES LTD. (IN) 2024-05-23 WO disclosed
WO-2024086259-A1 METHOD FOR PREPARING CHLORINE-CONTAINING BENZAMIDE DERIVATIVES FMC CORPORATION (US) 2024-04-25 WO disclosed
CN-117700393-A Preparation method of chlorantraniliprole 青岛科技大学 2024-03-15 CN disclosed
US-20050075372-A1 Method for controlling particular insect pest by applying anthranilamide compounds E. I. DU PONT DE NEMOURS AND COMPANY 2005-04-07 US disclosed
WO-2004111030-A1 METHOD FOR PREPARING FUSED OXAZINONES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2004-12-23 WO disclosed
US-20040209923-A1 Anthranilamide arthropodicide treatment FMC CORPORATION 2004-10-21 US disclosed
US-20040198984-A1 1-(3-halopyrid-2-yl)-3-substituted-5-((2,4-substituted-6-aminocarbonyl)phenylaminocarbonyl) pyrazoles insecticides FMC CORPORATION 2004-10-07 US disclosed
EP-1427285-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E. I. du Pont de Nemours and Company (US) 2004-06-16 EP disclosed
EP-1416796-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
EP-1416797-A1 ARTHROPODICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-12 EP disclosed
WO-2003024222-A1 ANTHRANILAMIDE ARTHROPODICIDE TREATMENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2003-03-27 WO disclosed
WO-2003015518-A1 METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed
WO-2003015519-A1 ARTHROPODICIDAL ANTHRANILAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040209923-A1 Anthranilamide arthropodicide treatment ANTXR2, ARF5, NPM1 LMNA 3468/4885F2 610/4885CFD 4249/4885
US-20040198984-A1 1-(3-halopyrid-2-yl)-3-substituted-5-((2,4-substituted-6-aminocarbonyl)phenylaminocarbonyl) pyrazoles insecticides CYP4B1, CYP1B1, CYP2E1 LMNA 3737/4885F2 425/4885CFD 2781/4885
US-20050075372-A1 Method for controlling particular insect pest by applying anthranilamide compounds ANTXR2, HRH4, HDAC10 LMNA 2915/4885F2 479/4885CFD 4858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.