Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343778 | 0.93 | ALOX15 (0.35) | TSHRALOX15ALOX12HIF1AHSD17B10 | |
| SCHEMBL6341910 | 0.89 | AKR1C2 (0.36) | TSHRALOX15ALOX12HIF1AHSD17B10 | |
| SCHEMBL6334648 | 0.81 | ALOX15 (0.42) | ALOX15ALOX12HSD17B10TDP1ALDH1A1 | |
| SCHEMBL6335356 | 0.78 | RPS6KA3 (0.44) | RPS6KA3 | |
| SCHEMBL11825346 | 0.78 | CA2 (0.48) | ALOX15HIF1AALDH1A1PTPN1CYP2C9 | |
| SCHEMBL6333445 | 0.78 | AKR1C2 (0.41) | TSHRHSD17B10CYP3A4ALDH1A1RECQL | |
| SCHEMBL6334695 | 0.76 | PTPN1 (0.40) | CYP3A4PIM1PTPN1CYP2C9MEN1 | |
| SCHEMBL6336087 | 0.76 | SMPD3 (0.40) | — | |
| SCHEMBL6337329 | 0.75 | RPS6KA3 (0.39) | TDP1RPS6KA3CYP2C9 | |
| SCHEMBL6343766 | 0.75 | CYP2C9 (0.56) | TSHRHIF1AHSD17B10CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050228167-A1 | Molecular compounds containing polymers having hydrogen bond sites as the constituent compounds | NIPPON SODA CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |