SCHEMBL634328

SCHEMBL634328

N#C/N=c1/nc(O)cc(O)[nH]1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
DUSP3 P51452 1/20 0.35
PTPN5 P54829 1/20 0.35
KMT2A Q03164 1/20 0.35
PTPN11 Q06124 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10429495 1.00 MEN1 (0.35) MEN1MAPTDUSP3PTPN5KMT2A
SCHEMBL16513237 0.81 MEN1 (0.33) MEN1MAPTDUSP3PTPN5KMT2A
SCHEMBL10429497 0.81 CYP3A4 (0.33)
SCHEMBL9505970 0.81 CYP3A4 (0.33)
SCHEMBL1487281 0.61
SCHEMBL2117025 0.56 MEN1 (0.35) MEN1MAPTDUSP3PTPN5KMT2A
SCHEMBL11227687 0.56 TTR (0.48) MEN1MAPTDUSP3PTPN5KMT2A
SCHEMBL5173757 0.53
SCHEMBL5173583 0.53
SCHEMBL2394640 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10392514-B2 Storage-stable dye solutions ARCHROMA IP GMBH (CH) 2019-08-27 US disclosed
EP-3122820-B1 STORAGE-STABLE DYE SOLUTIONS ARCHROMA IP GMBH (CH) 2019-03-13 EP disclosed
EP-3122820-A1 STORAGE-STABLE DYE SOLUTIONS Archroma IP GmbH (CH) 2017-02-01 EP disclosed
US-20170022366-A1 STORAGE-STABLE DYE SOLUTIONS ARCHROMA IP GMBH (CH) 2017-01-26 US disclosed
WO-2015144315-A1 STORAGE-STABLE DYE SOLUTIONS ARCHROMA IP GMBH (CH) 2015-10-01 WO disclosed
EP-1727863-B1 CONCENTRATED DYE SOLUTIONS CLARIANT FINANCE BVI LTD (VG) 2012-02-22 EP disclosed
US-7686851-B2 Concentrated dye solutions CLARIANT FINANCE (BVI) LIMITED (VG) 2010-03-30 US disclosed
US-20070186805-A1 Concentrated dye solutions ARCHROMA IP GMBH (CH) 2007-08-16 US disclosed
EP-1727863-A1 CONCENTRATED DYE SOLUTIONS Clariant International Ltd. (CH) 2006-12-06 EP disclosed
WO-2005087872-A1 CONCENTRATED DYE SOLUTIONS CLARIANT INTERNATIONAL LTD. (CH) 2005-09-22 WO disclosed
EP-0297397-B1 PREPARATION OF DIAZO AND AZO COMPOUNDS BAYER AG (DE) 1993-08-04 EP disclosed
EP-0262095-B1 ANIONIC DISAZO COMPUNDS SANDOZ AG (CH) 1990-12-27 EP disclosed
US-4942225-A Preparation of diazo and azo compounds using azidoformamidium salts BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed
US-4833235-A Sulfo group-containing disaz compounds having a heterocyclic coupling component radical SANDOZ LTD. (CH) 1989-05-23 US disclosed
EP-0297397-A2 Preparation of diazo and azo compounds BAYER AG (DE) 1989-01-04 EP disclosed
EP-0262095-A2 Anionic disazo compunds SANDOZ AG (CH) 1988-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392514-B2 Storage-stable dye solutions IK, G6PD, TYR MEN1 2734/4885MAPT 230/4885DUSP3 1844/4885
US-20170022366-A1 STORAGE-STABLE DYE SOLUTIONS IK, G6PD, TYR MEN1 2734/4885MAPT 230/4885DUSP3 1844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.