Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633026 | 0.89 | CCR2 (0.52) | CCR2 | |
| SCHEMBL633414 | 0.85 | CCR2 (0.47) | CCR2 | |
| SCHEMBL628694 | 0.84 | CCR2 (0.48) | CCR2 | |
| SCHEMBL629448 | 0.80 | CCR2 (0.41) | CCR2 | |
| SCHEMBL614631 | 0.77 | CCR2 (0.75) | CCR2 | |
| SCHEMBL629157 | 0.73 | CCR2 (0.48) | CCR2 | |
| Trifluoroacetic Acid SCHEMBL632228 | 0.73 | CCR2 (0.60) | CCR2 | |
| SCHEMBL3347918 | 0.71 | CCR2 (0.67) | CCR2 | |
| SCHEMBL3719908 | 0.71 | CCR2 (0.61) | CCR2 | |
| SCHEMBL633234 | 0.71 | CCR2 (0.53) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419419-A1 | 4-AZETIDINYL-1-PHENYL-CYCLOHEXANE ANTAGONISTS OF CCR2 | Janssen Pharmaceutica, N.V. (BE) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010121046-A1 | 4-AZETIDINYL-1-PHENYL-CYCLOHEXANE ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-21 | — | — | WO | disclosed |