Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6344077 | 0.91 | CREBBP (0.41) | CREBBPMEN1KMT2ACCNT1CDK9 | |
| SCHEMBL6339035 | 0.87 | MEN1 (0.51) | CREBBPMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6344466 | 0.84 | PRKCZ (0.35) | CCNT1CDK9PTGS2MAPTPRKCZ | |
| SCHEMBL6342677 | 0.83 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL6341045 | 0.81 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL6344215 | 0.81 | HDAC1 (0.36) | MAPTPRKCZTHRB | |
| SCHEMBL6340409 | 0.80 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL5654441 | 0.79 | CCR5 (0.45) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL6342839 | 0.77 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2HTTPOLB | |
| SCHEMBL6341807 | 0.77 | MEN1 (0.50) | CREBBPMEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936602-B1 | Benzazepine derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-30 | — | — | US | disclosed |
| EP-1186604-A1 | BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-13 | — | — | EP | disclosed |