Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 4/20 | 0.49 |
| ▸ | PRKCA | P17252 | 4/20 | 0.49 |
| ▸ | GSK3B | P49841 | 3/20 | 0.49 |
| ▸ | PRKCG | P05129 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127976 | 0.79 | GSK3B (0.56) | PRKCBPRKCAGSK3BPRKCGKCNH2 | |
| SCHEMBL3600677 | 0.77 | KDM4E (0.46) | PRKCBPRKCAGSK3BPRKCGPRKCD | |
| SCHEMBL4848432 | 0.75 | CDK2 (0.39) | PRKCBPRKCAGSK3BPRKCG | |
| SCHEMBL6344338 | 0.74 | GSK3B (0.41) | PRKCBPRKCAGSK3BPRKCGKCNH2 | |
| SCHEMBL29504831 | 0.72 | CCNE2 (0.63) | PRKCAGSK3B | |
| SCHEMBL5879232 | 0.72 | CCNE2 (0.63) | PRKCAGSK3B | |
| Hydrochloric Acid SCHEMBL29664072 | 0.71 | CCNE2 (0.61) | PRKCAGSK3B | |
| SCHEMBL3774109 | 0.70 | GSK3B (0.66) | PRKCBPRKCAGSK3BPRKCGKCNH2 | |
| SCHEMBL4847504 | 0.70 | PRKCG (0.41) | PRKCBPRKCAGSK3BPRKCGKCNH2 | |
| SCHEMBL2954257 | 0.69 | GSK3B (0.43) | PRKCBPRKCAGSK3BPRKCGPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849643-B2 | Indazolyl-substituted pyrroline compounds as kinase inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-02-01 | — | — | US | disclosed |