Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL634475

N.O=C1C=CC(Cl)=C(Cl)C1=O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPT P10636 4/20 0.36
HPGD P15428 4/20 0.36
KMT2A Q03164 4/20 0.36
ALOX12 P18054 3/20 0.36
RECQL P46063 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
ALOX15 P16050 3/20 0.35
HSD17B10 Q99714 3/20 0.35
BCHE P06276 3/20 0.35
ACHE P22303 3/20 0.35
CES1 P23141 3/20 0.35
TP53 P04637 2/20 0.35
CYP3A4 P08684 2/20 0.35
MAPK1 P28482 2/20 0.35
CES2 O00748 2/20 0.35
KDM4E B2RXH2 2/20 0.35
TSHR P16473 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10945354 0.97 MEN1 (0.38) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL299115 0.68 ALDH1A1 (0.47) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL6854819 0.67 MEN1 (0.41) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL28758918 0.65 ALDH1A1 (0.45) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL15603385 0.63
Chloranil SCHEMBL4624317 0.60 CES2 (0.90) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL6618539 0.57 MEN1 (0.38) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL187343 0.57 MEN1 (0.48) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL10945411 0.57 CES2 (0.42) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL10946387 0.57 MAPT (0.44) MEN1ALDH1A1MAPTHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10408786-B2 Distributable chemical sampling and sensing system ChemiSensor, LLP (US) 2019-09-10 US disclosed
US-20170336341-A1 Distributable Chemical Sampling and Sensing System ChemiSensor, LLP 2017-11-23 US disclosed
US-8668821-B2 Detection of phenols ISIS INNOVATION LIMITED (GB) 2014-03-11 US disclosed
US-20130334045-A1 Distributable Chemical Sampling and Sensing System ChemiSensor LLP (US) 2013-12-19 US disclosed
US-20130337477-A1 Distributable Chemical Sampling and Sensing System Process ChemiSensor LLP (US) 2013-12-19 US disclosed
US-20130098779-A1 Detection of Phenols ISIS INNOVATION LIMITED (GB) 2013-04-25 US disclosed
EP-1891423-B1 DETECTION OF PHENOLS ISIS INNOVATION (GB) 2012-02-22 EP disclosed
US-20090294298-A1 Detection of Phenols ISIS INNOVATION LIMITED (GB) 2009-12-03 US disclosed
EP-1891423-A1 DETECTION OF PHENOLS Isis Innovation Limited (GB) 2008-02-27 EP disclosed
WO-2006134386-A1 DETECTION OF PHENOLS ISIS INNOVATION LIMITED (GB) 2006-12-21 WO disclosed