Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343478 | 0.92 | LTA4H (0.32) | LTA4H | |
| SCHEMBL6344846 | 0.87 | LTA4H (0.33) | TSHRLTA4HNR5A1GAARAB9A | |
| SCHEMBL7546325 | 0.81 | KDM4E (0.41) | LTA4H | |
| SCHEMBL8599977 | 0.81 | LTA4H (0.53) | TSHRLTA4HNR5A1GAARAB9A | |
| SCHEMBL10998789 | 0.80 | LTA4H (0.52) | LTA4HGAAPPARG | |
| SCHEMBL10998787 | 0.80 | LTA4H (0.52) | LTA4HGAAPPARG | |
| SCHEMBL13439646 | 0.78 | ALDH1A1 (0.40) | TSHRPPARG | |
| SCHEMBL6004172 | 0.78 | LTA4H (0.34) | TSHRLTA4HNR5A1GAARAB9A | |
| SCHEMBL6343472 | 0.78 | LTA4H (0.30) | LTA4H | |
| SCHEMBL6694487 | 0.77 | TSHR (0.37) | TSHRGAARAB9ATP53PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936602-B1 | Benzazepine derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-08-30 | — | — | US | disclosed |
| EP-1186604-A1 | BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-03-13 | — | — | EP | disclosed |