Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.67 |
| ▸ | DRD3 | P35462 | 13/20 | 0.67 |
| ▸ | DRD4 | P21917 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6335392 | 1.00 | DRD2 (0.67) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL6344103 | 0.96 | DRD3 (0.67) | DRD2DRD3DRD4 | |
| SCHEMBL6342758 | 0.91 | DRD2 (0.56) | DRD2DRD3DRD4LMNA | |
| SCHEMBL6336491 | 0.91 | DRD3 (0.54) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL6334439 | 0.89 | DRD2 (0.62) | DRD2DRD3DRD4HTR1A | |
| SCHEMBL6334412 | 0.88 | ALDH1A1 (0.51) | DRD2DRD3DRD4CYP2D6 | |
| SCHEMBL6343679 | 0.88 | DRD2 (0.56) | DRD2DRD3DRD4LMNA | |
| SCHEMBL9558523 | 0.88 | DRD2 (0.83) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL3390085 | 0.87 | DRD3 (0.53) | DRD2DRD3DRD4MEN1KMT2A | |
| SCHEMBL6334883 | 0.87 | DRD3 (0.48) | DRD2DRD3DRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864266-B2 | 4-piperidinyl alkyl amine derivatives as muscarinic receptor antagonists | SYNTEX (U.S.A.) LLC (US) | 2005-03-08 | — | — | US | claimed |