SCHEMBL634543

SCHEMBL634543

c1ccc2c3c(ccc2c1)CCN3

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42
CYP2A6 P11509 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HPRT1 P00492 1/20 0.39
PARP1 P09874 2/20 0.37
PDPK1 O15530 1/20 0.37
PARP10 Q53GL7 1/20 0.37
PARP11 Q9NR21 1/20 0.37
HTR2C P28335 2/20 0.37
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
NISCH Q9Y2I1 2/20 0.36
CYP3A4 P08684 1/20 0.34
HTR3E A5X5Y0 1/20 0.34
HTR3B O95264 1/20 0.34
CYP1A2 P05177 1/20 0.34
HTR1A P08908 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31668742 1.00 HSD17B10 (0.42) HSD17B10ALDH1A1TSHRCYP2A6TDP1
Iodide SCHEMBL29247920 0.98 HSD17B10 (0.41) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL8714223 0.91 HPRT1 (0.50) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL31456577 0.91 HPRT1 (0.50) HSD17B10ALDH1A1TSHRCYP2A6TDP1
Hydrochloric Acid SCHEMBL8713800 0.89 HPRT1 (0.48) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL6725176 0.89 CXCR4 (0.40) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL28732081 0.81 NPC1 (0.58) HSD17B10ALDH1A1PARP1PDPK1PARP10
SCHEMBL12799615 0.81 HSD17B10 (0.39) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL21187674 0.80 HPRT1 (0.47) HSD17B10ALDH1A1TSHRCYP2A6TDP1
SCHEMBL4421747 0.79 ALDH1A1 (0.46) HSD17B10ALDH1A1TSHRCYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4304842-B1 METHOD FOR MAKING PHOTOFUNCTIONAL CONTACT LENSES ALCON INC (CH) 2026-05-06 EP claimed
EP-4347683-B1 CURABLE PHOTOCHROMIC COMPOSITION TRANSITIONS OPTICAL LTD (IE) 2026-05-06 EP claimed
EP-4727984-A1 CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING (METH)ACRYLATE, AMINE, AND ISOCYANATE FUNCTIONAL COMPONENTS Transitions Optical, Ltd. (IE) 2026-04-22 EP claimed
US-12570787-B2 Curable compositions and articles prepared therefrom TRANSITIONS OPTICAL, LTD. (IE) 2026-03-10 US claimed
US-20250361353-A1 Curable Photochromic Compositions Including Isocyanate and Imine Functional Components TRANSITIONS OPTICAL LTD (IE) 2025-11-27 US claimed
EP-4562458-A1 CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING HYDRAZIDE AND CARBONYL FUNCTIONAL COMPONENTS Transitions Optical, Ltd. (IE) 2025-06-04 EP claimed
CN-118420518-B Benzondolium salt and preparation method and application thereof 南通大学附属医院 2025-05-09 CN claimed
EP-4547724-A1 CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING ISOCYANATE AND IMINE FUNCTIONAL COMPONENTS Transitions Optical, Ltd. (IE) 2025-05-07 EP claimed
WO-2025070233-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, AND METHOD FOR PRODUCING CURED PRODUCT 東レ株式会社 2025-04-03 WO claimed
US-12247169-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2025-03-11 US claimed
EP-0800522-B1 PHOTOCHROMIC DIARYL-3H-NAPHTHOPYRANES RODENSTOCK OPTIK G (DE) 2002-02-20 EP claimed
WO-2001004702-A1 DRY PHOTOGRAPHIC PRINTING PROCESS KROMOTEK LTD (IL) 2001-01-18 WO claimed
US-5990305-A Photochromic diaryl-3H-naphthopyrane OPTISCHE WERKE G. RODENSTOCK (DE) 1999-11-23 US claimed
US-5808044-A Indocarbocyanine and benzindocarbocyanine phosphoramidites PHARMACIA BIOTECH INC. (US) 1998-09-15 US claimed
EP-0800522-A2 PHOTOCHROMIC DIARYL-3H-NAPHTHOPYRANES Optische Werke G. Rodenstock (DE) 1997-10-15 EP claimed
WO-1997015565-A9 PHOTOCHROMIC DIARYL-3H-NAPHTHOPYRANES 1997-07-17 WO claimed
WO-1997015565-A2 PHOTOCHROMIC DIARYL-3H-NAPHTHOPYRANES OPTISCHE WERKE G. RODENSTOCK (DE) 1997-05-01 WO claimed
EP-0272212-B1 PROCESS FOR CONTINUALLY PRODUCING AZO OR HYDRAZONE DYES CIBA-GEIGY AG (CH) 1993-09-01 EP claimed
US-4925926-A Preparation of cationic azo or hydrazone dyes in which the alkylation and the separation of the cationic dye are carried out continuously CIBA-GEIGY CORPORATION (US) 1990-05-15 US claimed
EP-0272212-A2 Process for continually producing azo or hydrazone dyes CIBA-GEIGY AG (CH) 1988-06-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570787-B2 Curable compositions and articles prepared therefrom EHMT2, EHMT1, BHMT2 HSD17B10 2919/4885ALDH1A1 1039/4885TSHR 3505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.