Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22974957 | 0.88 | GPR119 (0.41) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL3663435 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KDM4ECYP2C19CYP2D6TSHR | |
| SCHEMBL23908385 | 0.82 | CYP2D6 (0.53) | ALDH1A1CYP3A4CYP2C19CYP2D6TSHR | |
| SCHEMBL180293 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4ECYP2D6GAASTAT3 | |
| SCHEMBL6775330 | 0.81 | — | — | |
| SCHEMBL14994148 | 0.81 | CYP2D6 (0.40) | ALDH1A1KDM4EMAPK1ATMCYP3A4 | |
| SCHEMBL14994147 | 0.81 | CYP2D6 (0.40) | ALDH1A1KDM4EMAPK1ATMCYP3A4 | |
| SCHEMBL25418266 | 0.80 | CYP2D6 (0.45) | ALDH1A1KDM4ECYP2D6TSHRGAA | |
| SCHEMBL3834098 | 0.80 | CYP2D6 (0.45) | ALDH1A1KDM4ECYP2D6TSHRGAA | |
| SCHEMBL26907053 | 0.80 | CYP2D6 (0.45) | ALDH1A1KDM4ECYP2D6TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785707-B1 | NOVEL 2H-INDAZOLES AS EP2 RECEPTOR ANTAGONISTS | BAYER IP GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |
| US-9655887-B2 | Pharmaceutical composition and the use thereof, and application regime of said pharmaceutical composition for on-demand contraception | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-05-23 | — | — | US | disclosed |
| US-20160089364-A1 | PHARMACEUTICAL COMPOSITION AND THE USE THEREOF, AND APPLICATION REGIME OF SAID PHARMACEUTICAL COMPOSITION FOR ON-DEMAND CONTRACEPTION | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-03-31 | — | — | US | disclosed |
| EP-2999469-A1 | PHARMACEUTICAL COMPOSITION AND THE USE THEREOF, AND APPLICATION REGIME OF SAID PHARMACEUTICAL COMPOSITION FOR ON-DEMAND CONTRACEPTION | Bayer Pharma Aktiengesellschaft (DE) | 2016-03-30 | — | — | EP | disclosed |
| US-9062041-B2 | 2H-indazoles as EP2 receptor antagonists | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-23 | — | — | US | disclosed |
| WO-2014187744-A1 | PHARMACEUTICAL COMPOSITION AND THE USE THEREOF, AND APPLICATION REGIME OF SAID PHARMACEUTICAL COMPOSITION FOR ON-DEMAND CONTRACEPTION | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-11-27 | — | — | WO | disclosed |
| US-20140336172-A1 | Novel 2H-Indazoles as EP2 Receptor Antagonists | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-11-13 | — | — | US | disclosed |
| EP-2785707-A1 | NOVEL 2H-INDAZOLES AS EP2 RECEPTOR ANTAGONISTS | Bayer Intellectual Property GmbH (DE) | 2014-10-08 | — | — | EP | disclosed |
| WO-2013079425-A1 | NOVEL 2H-INDAZOLES AS EP2 RECEPTOR ANTAGONISTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-06 | — | — | WO | disclosed |
| EP-2419413-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119992-A1 | DERIVATIVES OF N-ACYL-N'-PHENYLPIPERAZINE USEFUL (INTER ALIA) FOR THE PROPHYLAXIS OR TREATMENT OF DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160089364-A1 | PHARMACEUTICAL COMPOSITION AND THE USE THEREOF, AND APPLICATION REGIME OF SAID PHARMACEUTICAL COMPOSITION FOR ON-DEMAND CONTRACEPTION | PTGER2, PTGER3, PTGER1 | ALDH1A1 2559/4885KDM4E 3312/4885MAPK1 4324/4885 |
| US-20140336172-A1 | Novel 2H-Indazoles as EP2 Receptor Antagonists | PTGER2, PTGER1, PTGDR2 | ALDH1A1 815/4885KDM4E 3850/4885MAPK1 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.