Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7745827 | 0.85 | SRC (0.47) | SRCMAPTALOX15SMN1; SMN2KDM4E | |
| SCHEMBL16904957 | 0.85 | SRC (0.54) | SRCMAPTALOX15SMN1; SMN2KDM4E | |
| SCHEMBL8930270 | 0.85 | SRC (0.54) | SRCMAPTALOX15SMN1; SMN2KDM4E | |
| SCHEMBL1802839 | 0.81 | KDM4E (0.47) | MAPTKDM4EALDH1A1PTGS2MEN1 | |
| Ethylenediamine SCHEMBL14844383 | 0.79 | SRC (0.56) | SRCMAPTALOX15SMN1; SMN2KDM4E | |
| SCHEMBL1802835 | 0.79 | KDM4E (0.48) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28259770 | 0.79 | BCL2 (0.46) | MAPTKDM4EALDH1A1PTGS2MEN1 | |
| SCHEMBL29481933 | 0.78 | SRC (0.62) | SRCMAPTALOX15SMN1; SMN2KDM4E | |
| SCHEMBL3228305 | 0.78 | SRC (0.62) | SRCMAPTALOX15SMN1; SMN2KDM4E | |
| SCHEMBL1807383 | 0.78 | KDM4E (0.44) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058977-A1 | Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof | INSTITUTE OF MATERIA MEDIC, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2004-03-25 | — | — | US | claimed |
| US-6960611-B2 | Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof | INSTITUTE OF MATERIA MEDICA (CN) | 2005-11-01 | — | — | US | disclosed |
| US-20040058977-A1 | Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof | INSTITUTE OF MATERIA MEDIC, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2004-03-25 | — | — | US | disclosed |
| EP-0205348-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| US-4889550-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-12-26 | — | — | US | disclosed |
| US-4786314-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| US-4678498-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0205348-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058977-A1 | Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof | PTGS2, PTGES2, PTGER2 | SRC 1851/4885MAPT 4789/4885ALOX15 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.